Endothelin-1 (human, porcine) (trifluoroacetate salt)
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- $415 - $744
- Product name: Endothelin-1 (human, porcine) (trifluoroacetate salt)
- CAS:
- MF: C111H160F3N25O34S5
- MW: 2605.9254096
- EINECS:
- MDL Number:
- Synonyms:Endothelin-1 (human, porcine) (trifluoroacetate salt)
2 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 500μg
- 1mg
- ManufacturerCayman Chemical
- Product number24127
- Product descriptionEndothelin-1 (human, porcine) (trifluoroacetate salt) ≥95%
- Packaging500μg
- Price$415
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number24127
- Product descriptionEndothelin-1 (human, porcine) (trifluoroacetate salt) ≥95%
- Packaging1mg
- Price$744
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 24127 | Endothelin-1 (human, porcine) (trifluoroacetate salt) ≥95% | 500μg | $415 | 2026-04-30 | Buy |
| Cayman Chemical | 24127 | Endothelin-1 (human, porcine) (trifluoroacetate salt) ≥95% | 1mg | $744 | 2026-04-30 | Buy |
Properties
solubility :Formic Acid: 1 mg/ml
Safety Information
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Description
Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively).1,2 It induces contraction of pig coronary artery strips (EC50 = 0.52 nM), vasoconstriction of pig cardiac ventricular membrane (120% of control), and increases mean early pressor phase blood pressure by 66 mg Hg in rats when administered at a dose of 1 nmol/kg. In an inducible system of endothelium-restricted overexpression of human endothelin-1, induction of endothelin-1 increases blood pressure in mice.3 It stabilizes and induces nuclear translocation of hypoxia-inducible factor 1 and 2 alpha (HIF-1α and HIF-2α) via ETB in human lymphatic endothelial cells.4 Endothelin-1 autocrine and paracrine signaling modulates cell proliferation, apoptosis, migration, and epithelial-to-mesenchymal transition, suggesting a role in cancer.5WARNING This product is not for human or veterinary use.More related product prices