CPI-444
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- $44 - $2500
- Product name: CPI-444
- CAS: 1202402-40-1
- MF: C20H21N7O3
- MW: 407.43
- EINECS:-0
- MDL Number:MFCD31540410
- Synonyms:CPI-444;CPI 444;CPI444;(S)-7-(5-Methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine;CS-2828;Ciforadenant;(S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyriMidin-5-ylaMine;CPD1110;CPI-444;7-(5-Methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine
15 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number3392DF
- Product descriptionCiforadenant
- Packaging1mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3392DF
- Product descriptionCiforadenant
- Packaging10mg
- Price$407
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0005711
- Product description(S)-7-(5-METHYLFURAN-2-YL)-3-((6-(((TETRAHYDROFURAN-3-YL)OXY)METHYL)PYRIDIN-2-YL)METHYL)-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE 95.00%
- Packaging5MG
- Price$454.51
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25024
- Product descriptionCPI-444 ≥98%
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25024
- Product descriptionCPI-444 ≥98%
- Packaging5mg
- Price$151
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25024
- Product descriptionCPI-444 ≥98%
- Packaging10mg
- Price$278
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25024
- Product descriptionCPI-444 ≥98%
- Packaging25mg
- Price$638
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-7627
- Product descriptionCPI-444 99.94%
- Packaging5mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7627
- Product descriptionCPI-444 99.94%
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7627
- Product descriptionCPI-444 99.94%
- Packaging50mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7627
- Product descriptionCPI-444 99.94%
- Packaging100mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10527
- Product descriptionCPI-444 >98%
- Packaging100mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10527
- Product descriptionCPI-444 >98%
- Packaging1g
- Price$2500
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC781455
- Product descriptionCPI-444
- Packaging25mg
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC781455
- Product descriptionCPI-444
- Packaging100mg
- Price$1040
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3392DF | Ciforadenant | 1mg | $147 | 2021-12-16 | Buy |
| AK Scientific | 3392DF | Ciforadenant | 10mg | $407 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0005711 | (S)-7-(5-METHYLFURAN-2-YL)-3-((6-(((TETRAHYDROFURAN-3-YL)OXY)METHYL)PYRIDIN-2-YL)METHYL)-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-5-AMINE 95.00% | 5MG | $454.51 | 2021-12-16 | Buy |
| Cayman Chemical | 25024 | CPI-444 ≥98% | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 25024 | CPI-444 ≥98% | 5mg | $151 | 2024-03-01 | Buy |
| Cayman Chemical | 25024 | CPI-444 ≥98% | 10mg | $278 | 2024-03-01 | Buy |
| Cayman Chemical | 25024 | CPI-444 ≥98% | 25mg | $638 | 2024-03-01 | Buy |
| ChemScene | CS-7627 | CPI-444 99.94% | 5mg | $100 | 2021-12-16 | Buy |
| ChemScene | CS-7627 | CPI-444 99.94% | 10mg | $150 | 2021-12-16 | Buy |
| ChemScene | CS-7627 | CPI-444 99.94% | 50mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-7627 | CPI-444 99.94% | 100mg | $750 | 2021-12-16 | Buy |
| DC Chemicals | DC10527 | CPI-444 >98% | 100mg | $700 | 2021-12-16 | Buy |
| DC Chemicals | DC10527 | CPI-444 >98% | 1g | $2500 | 2021-12-16 | Buy |
| TRC | C781455 | CPI-444 | 25mg | $450 | 2021-12-16 | Buy |
| TRC | C781455 | CPI-444 | 100mg | $1040 | 2021-12-16 | Buy |
Properties
Melting point :169-171°C
Boiling point :676.9±65.0 °C(Predicted)
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :4.05±0.30(Predicted)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :KURQKNMKCGYWRJ-HNNXBMFYSA-N
SMILES :C1(N)=NC(C2=CC=C(C)O2)=C2N=NN(CC3=NC(CO[C@H]4CCOC4)=CC=C3)C2=N1
Boiling point :676.9±65.0 °C(Predicted)
Density :1.55±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :4.05±0.30(Predicted)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :KURQKNMKCGYWRJ-HNNXBMFYSA-N
SMILES :C1(N)=NC(C2=CC=C(C)O2)=C2N=NN(CC3=NC(CO[C@H]4CCOC4)=CC=C3)C2=N1
Safety Information
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Description
CPI-444 (1202402-40-1) is a potent (Ki = 3.54 nM) and selective adenosine A2A receptor antagonist. It blocked the induction of cAMP induced by NECA in HEK-293 cells with an IC50 = 17.03 nM. CPI-444 monotherapy or in combination with anti-PD-1, anti-PD-L1, and anti-CTLA-4 induced T-cell-mediated tumor responses, inhibited tumor growth, and enabled antitumor immune memory. Currently in clinical trials for multiple cancers.Related product price
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![(S)-7-(5-Methyl-furan-2-yl)-3-[6-(tetrahydro-furan-3-yloxyMethyl)-pyridin-2-ylMethyl]-3H-[1,2,3]triazolo[4,5-d]pyriMidin-5-ylaMine](https://img.chemicalbook.com/ProductImageEN/2019-8/small/5cb209a9-e5a3-43fd-9135-752a720bab90.jpg){kind=small}