FIPI
|
- $49 - $2691.1
- Product name: FIPI
- CAS: 939055-18-2
- MF: C23H24FN5O2
- MW: 421.47
- EINECS:
- MDL Number:MFCD18382115
- Synonyms:FIPI;FIPI HYDROCHLORIDE;5-Fluoro-2-Indolyl des-Chlorohalopemide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-1H-indole-2-carboxamide;N-[2-[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethy]-5-fluoro-1H-indole-2-carboxamide hydrochloride;CS-1511; 5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide;1H-Indole-2-carboxamide, N-[2-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-5-fluoro-
41 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO
- 1mg
- 10
- 2mg
- 5mg
- 10mg
- 50
- 25mg
- 50mg
- 100MG
- 250mg
- 1g
- 1000mg
- 5 mg
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide ≥98%
- Packaging1mg
- Price$49
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide
- Packaging2mg
- Price$54
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide
- Packaging5mg
- Price$75
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide
- Packaging10mg
- Price$92
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide
- Packaging25mg
- Price$166
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00GT85
- Product description5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide
- Packaging50mg
- Price$275
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD251471
- Product descriptionFIPI 98%
- Packaging100MG
- Price$260
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD251471
- Product descriptionFIPI 98%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0105888
- Product descriptionN-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00%
- Packaging5MG
- Price$498.97
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7440
- Product descriptionFIPI
- Packaging25mg
- Price$273
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7440
- Product descriptionFIPI
- Packaging5mg
- Price$95
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7440
- Product descriptionFIPI
- Packaging10mg
- Price$144
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-12807
- Product descriptionFIPI 98.00%
- Packaging10mg
- Price$154
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12807
- Product descriptionFIPI 98.00%
- Packaging5mg
- Price$119
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12807
- Product descriptionFIPI 98.00%
- Packaging50mg
- Price$490
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-12807
- Product descriptionFIPI 98.00%
- Packaging25mg
- Price$308
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide ≥98% | 1mg | $49 | 2026-05-28 | Buy |
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide | 2mg | $54 | 2026-05-28 | Buy |
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide | 5mg | $75 | 2026-05-28 | Buy |
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide | 10mg | $92 | 2026-05-28 | Buy |
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide | 25mg | $166 | 2026-05-28 | Buy |
| aablocks | AA00GT85 | 5-Fluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide | 50mg | $275 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD251471 | FIPI 98% | 100MG | $260 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD251471 | FIPI 98% | 25MG | $110 | 2026-05-27 | Buy |
| American Custom Chemicals Corporation | HCH0105888 | N-(2-(4-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)-1-PIPERIDINYL)ETHYL)-5-FLUORO-1H-INDOLE-2-CARBOXAMIDE 95.00% | 5MG | $498.97 | 2021-12-16 | Buy |
| ApexBio Technology | B7440 | FIPI | 25mg | $273 | 2026-05-06 | Buy |
| ApexBio Technology | B7440 | FIPI | 5mg | $95 | 2026-05-06 | Buy |
| ApexBio Technology | B7440 | FIPI | 10mg | $144 | 2026-05-06 | Buy |
| Arctom | HY-12807 | FIPI 98.00% | 10mg | $154 | 2026-05-26 | Buy |
| Arctom | HY-12807 | FIPI 98.00% | 5mg | $119 | 2026-05-26 | Buy |
| Arctom | HY-12807 | FIPI 98.00% | 50mg | $490 | 2026-05-26 | Buy |
| Arctom | HY-12807 | FIPI 98.00% | 25mg | $308 | 2026-05-26 | Buy |
Properties
Density :1.349±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form :Powder
pka :12.04±0.30(Predicted)
color :Light yellow to khaki
SMILES :O=C(C1=CC2=C(C=CC(F)=C2)N1)NCCN3CCC(N4C(NC5=C4C=CC=C5)=O)CC3
storage temp. :Store at -20°C
solubility :DMSO : 14.67 mg/mL (34.81 mM; Need ultrasonic and warming)
form :Powder
pka :12.04±0.30(Predicted)
color :Light yellow to khaki
SMILES :O=C(C1=CC2=C(C=CC(F)=C2)N1)NCCN3CCC(N4C(NC5=C4C=CC=C5)=O)CC3
Safety Information
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Description
Isoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM). It also prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. FIPI has good pharmacokinetic parameters in rats, with a half-life greater than five hours, a Cmax that, at 363 nM, is greater than 10-fold the IC50 versus PLD2, and bioavailability of 18%.More related product prices
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