FLI-06
|
- $44 - $3791
- Product name: FLI-06
- CAS: 313967-18-9
- MF: C25H30N2O5
- MW: 438.52
- EINECS:-0
- MDL Number:MFCD00330996
- Synonyms:FLI-06;1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid cyclohexyl ester;1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylic acid cyclohexyl ester FLI-06;3-QUINOLINECARBOXYLIC ACID, 1,4,5,6,7,8-HEXAHYDRO-2,7,7-TRIMETHYL-4-(4-NITROPHENYL)-5-OXO-, CYCLOHEXYL ESTER;FLI-06, 98%, a notch signaling and the early secretory pathway inhibitor;FLI-06 |FLI06;Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate;CS-1434
67 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Alichem
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 0.5g
- 500mg
- 1000mg
- 1G
- 10mM*1mLinDMSO(Solution)
- 10mM(in 1mL DMSO)
- 5G
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99
- Packaging1mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99%
- Packaging5mg
- Price$51
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99%
- Packaging10mg
- Price$77
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99%
- Packaging25mg
- Price$105
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99%
- Packaging50mg
- Price$126
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C6CS
- Product descriptionCyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99%
- Packaging100mg
- Price$151
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65713
- Product descriptioncyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98%
- Packaging250MG
- Price$220
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65713
- Product descriptioncyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98%
- Packaging1G
- Price$460
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65713
- Product descriptioncyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98%
- Packaging5G
- Price$1840
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2412AH
- Product descriptionCyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
- Packaging1g
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2412AH
- Product descriptionCyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate
- Packaging100mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number313967189
- Product description1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester
- Packaging1g
- Price$1685
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number313967189
- Product description1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester
- Packaging250mg
- Price$680
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number313967189
- Product description1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester
- Packaging500mg
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004775
- Product description2,7,7-TRIMETHYL-4-(4-NITRO-PHENYL)-5-OXO-1,4,5,6,7,8-HEXAHYDRO-QUINOLINE-3-CARBOXYLIC ACID CYCLOHEXYL ESTER 95.00%
- Packaging5MG
- Price$496.87
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB3083
- Product descriptionFLI-06
- Packaging10mM(in 1mL DMSO)
- Price$165
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99 | 1mg | $44 | 2026-05-28 | Buy |
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99% | 5mg | $51 | 2026-05-28 | Buy |
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99% | 10mg | $77 | 2026-05-28 | Buy |
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99% | 25mg | $105 | 2026-05-28 | Buy |
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99% | 50mg | $126 | 2026-05-28 | Buy |
| aablocks | AA00C6CS | Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate 99% | 100mg | $151 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65713 | cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98% | 250MG | $220 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65713 | cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98% | 1G | $460 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65713 | cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 98% | 5G | $1840 | 2026-05-27 | Buy |
| AK Scientific | 2412AH | Cyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate | 1g | $547 | 2021-12-16 | Buy |
| AK Scientific | 2412AH | Cyclohexyl2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate | 100mg | $168 | 2021-12-16 | Buy |
| Alichem | 313967189 | 1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester | 1g | $1685 | 2021-12-16 | Buy |
| Alichem | 313967189 | 1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester | 250mg | $680 | 2021-12-16 | Buy |
| Alichem | 313967189 | 1,4,5,6,7,8-Hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylicacidcyclohexylester | 500mg | $980 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004775 | 2,7,7-TRIMETHYL-4-(4-NITRO-PHENYL)-5-OXO-1,4,5,6,7,8-HEXAHYDRO-QUINOLINE-3-CARBOXYLIC ACID CYCLOHEXYL ESTER 95.00% | 5MG | $496.87 | 2021-12-16 | Buy |
| ApexBio Technology | B3083 | FLI-06 | 10mM(in 1mL DMSO) | $165 | 2021-12-16 | Buy |
Properties
Melting point :199-202oC
Boiling point :597.5±50.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :0.78±0.70(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChI :1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
InChIKey :SWWVFYHSSOWZMF-UHFFFAOYSA-N
SMILES :[N+](=O)([O-])c1ccc(cc1)C2C3=C(NC(=C2C(=O)OC4CCCCC4)C)CC(CC3=O)(C)C
Boiling point :597.5±50.0 °C(Predicted)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :0.78±0.70(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChI :1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
InChIKey :SWWVFYHSSOWZMF-UHFFFAOYSA-N
SMILES :[N+](=O)([O-])c1ccc(cc1)C2C3=C(NC(=C2C(=O)OC4CCCCC4)C)CC(CC3=O)(C)C
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
FLI-06 (313967-18-9) was discovered in a screen designed to monitor the trafficking and processing of a ligand-independent Notch-enhanced GFP reporter. It was found to disrupt the Golgi apparatus in a manner distinct from that of brefeldin A. It inhibited general secretion at a step before exit from the ER which was accompanied by a tubule-to-sheet morphological transition of the ER. Thus FLI-06 is the first small molecule acting at such an early stage in secretory traffic.1More related product prices
252917-06-9 RO4929097 LY411575 Semagacestat xav-939 SGC-GAK-1 304684-77-3 KPT-330 DIBENZAZEPINERelated product price
-
252917-06-9
$28-4401 -
RO4929097
$11-9435.2 -
LY411575
$34-4023.9
Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
ShangHai YuanYe Biotechnology Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
AdooQ BioScience, LLC
Bide Pharmatech Ltd.
AdooQ Bioscience CHINA
Taizhou Crene Biotechnology Co., Ltd.
Credit Asia Chemical Co., Ltd.
Hubei Jusheng Technology Co.,Ltd