Flumazenil
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- $12 - $2090
- Product name: Flumazenil
- CAS: 78755-81-4
- MF: C15H14FN3O3
- MW: 303.29
- EINECS:616-650-9
- MDL Number:MFCD00242764
- Synonyms:ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4h-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate;FLUMAZENIL;FluMazenil USP;8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE-3-CARBOXYLIC ACID ETHYL ESTER;8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO-4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID ETHYL EST;RO 15-1788;FLUMAZENIL;RO 15-1788; RO15-1788;;Flumazenil、Flumazepil
89 prices
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Brand
- aablocks
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 100.00mg
- 10mM*1mLinDMSO(Solution)
- 500mg
- 10g
- 10
- 50
- 200mg
- 250.00mg
- 1.00g
- 10mM*1mLinDMSO(Solid+Solvent)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 0.5g
- 1g
- 5g
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
- Packaging100mg
- Price$57
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
- Packaging250mg
- Price$79
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
- Packaging50mg
- Price$37
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
- Packaging10mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
- Packaging5mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95%
- Packaging1mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
- Packaging1g
- Price$196
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA005JC9
- Product descriptionEthyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98%
- Packaging5g
- Price$874
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226294
- Product descriptionFlumazenil 97.00%
- Packaging5G
- Price$1340
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY226294
- Product descriptionFlumazenil 97.00%
- Packaging1G
- Price$385
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberMT-51819
- Product descriptionFlumazenil 98%
- Packaging0.5g
- Price$530
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-51819
- Product descriptionFlumazenil 97%
- Packaging0.5g
- Price$530
- Updated2026-05-25
- Buy
- ManufacturerAHH
- Product numberMT-51819
- Product descriptionFlumazenil 97%
- Packaging0.5g
- Price$530
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberJ99861
- Product descriptionFlumazenil
- Packaging250mg
- Price$127
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ99861
- Product descriptionFlumazenil
- Packaging5g
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA423241
- Product descriptionFlumazenil 95+%
- Packaging250mg
- Price$66
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% | 100mg | $57 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% | 250mg | $79 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% | 50mg | $37 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% | 10mg | $25 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% | 5mg | $19 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 95% | 1mg | $12 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% | 1g | $196 | 2026-05-28 | Buy |
| aablocks | AA005JC9 | Ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 98% | 5g | $874 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y226294 | Flumazenil 97.00% | 5G | $1340 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y226294 | Flumazenil 97.00% | 1G | $385 | 2026-05-27 | Buy |
| AHH | MT-51819 | Flumazenil 98% | 0.5g | $530 | 2021-12-16 | Buy |
| AHH | MT-51819 | Flumazenil 97% | 0.5g | $530 | 2026-05-25 | Buy |
| AHH | MT-51819 | Flumazenil 97% | 0.5g | $530 | 2026-05-26 | Buy |
| AK Scientific | J99861 | Flumazenil | 250mg | $127 | 2021-12-16 | Buy |
| AK Scientific | J99861 | Flumazenil | 5g | $1200 | 2021-12-16 | Buy |
| Ambeed | A423241 | Flumazenil 95+% | 250mg | $66 | 2021-12-16 | Buy |
Properties
Melting point :201-203°C
Boiling point :528.0±50.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO to 25mM
form :solid
pka :0.86±0.20(Predicted)
color :white
Water Solubility :128 mg/L
Merck :14,4135
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChIKey :OFBIFZUFASYYRE-UHFFFAOYSA-N
SMILES :N12C=NC(C(OCC)=O)=C1CN(C)C(=O)C1=CC(F)=CC=C12
CAS DataBase Reference :78755-81-4(CAS DataBase Reference)
NIST Chemistry Reference :Flumazenil(78755-81-4)
Boiling point :528.0±50.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO to 25mM
form :solid
pka :0.86±0.20(Predicted)
color :white
Water Solubility :128 mg/L
Merck :14,4135
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Major Application :pharmaceutical (small molecule)
InChI :InChI=1S/C15H14FN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3
InChIKey :OFBIFZUFASYYRE-UHFFFAOYSA-N
SMILES :N12C=NC(C(OCC)=O)=C1CN(C)C(=O)C1=CC(F)=CC=C12
CAS DataBase Reference :78755-81-4(CAS DataBase Reference)
NIST Chemistry Reference :Flumazenil(78755-81-4)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Flumazenil is an imidazobenzodiazepine derivative that competitively inhibits benzodiazepine binding to GABAA receptors with an IC50 value of 2 nM. Flumazenil is non-selective for α1, α2, α3, or α5 subunit-containing GABAA receptors and antagonizes the actions of benzodiazepines on the central nervous system without producing the behavioral or neurological effects typical of the benzodiazepines. Flumazenil has been used to reverse sedation induced by benzodiazepine drugs and has been found to be effective in the treatment of benzodiazepine overdose or withdrawal.More related product prices
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