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ChemicalBook >> CAS DataBase List >> Lacosamide

Lacosamide

Lacosamide price.
  • $49 - $800
  • Product name: Lacosamide
  • CAS: 175481-36-4
  • MF: C13H18N2O3
  • MW: 250.29
  • EINECS:605-756-0
  • MDL Number:MFCD08272557
  • Synonyms:LACOSAMIDE;(2R)-2-acetamido-N-benzyl-3-methoxy-propanamide;(2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide;ADD 243037;Erlosamide;Harkoseride;SPM 927;(R)-2-Acetamido-N-benzyl-3-methoxypropanamide
Price20 Properties Safety Information Description
20 prices
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Brand
  • Axon Medchem
  • Biosynth
  • Cayman Chemical
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1mL
  • 10mM*1mLinDMSO
  • 1g
  • 5 mg
  • 25 mg
  • ManufacturerAxon Medchem
  • Product numberAxon1444
  • Product descriptionLacosamide 99%
  • Packaging10mg
  • Price$82.5
  • Updated2026-05-19
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1444
  • Product descriptionLacosamide 99%
  • Packaging50mg
  • Price$220
  • Updated2026-05-19
  • Buy
  • ManufacturerBiosynth
  • Product numberBL164605
  • Product descriptionLacosamide
  • Packaging50mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberBL164605
  • Product descriptionLacosamide
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging5mg
  • Price$54
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging10mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging10mg
  • Price$96
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging50mg
  • Price$278
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging25mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging25mg
  • Price$168
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10012592
  • Product descriptionLacosamide ≥98%
  • Packaging50mg
  • Price$306
  • Updated2026-04-30
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8797
  • Product descriptionLacosamide >98%
  • Packaging250mg
  • Price$400
  • Updated2026-05-24
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8797
  • Product descriptionLacosamide >98%
  • Packaging1g
  • Price$800
  • Updated2026-05-24
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8797
  • Product descriptionLacosamide >98%
  • Packaging100mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8797
  • Product descriptionLacosamide >98%
  • Packaging100mg
  • Price$200
  • Updated2026-05-24
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Axon Medchem Axon1444 Lacosamide 99% 10mg $82.5 2026-05-19 Buy
Axon Medchem Axon1444 Lacosamide 99% 50mg $220 2026-05-19 Buy
Biosynth BL164605 Lacosamide 50mg $175 2021-12-16 Buy
Biosynth BL164605 Lacosamide 10mg $68 2021-12-16 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 5mg $54 2026-04-30 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 10mg $87 2024-03-01 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 10mg $96 2026-04-30 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 50mg $278 2024-03-01 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 25mg $152 2024-03-01 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 25mg $168 2026-04-30 Buy
Cayman Chemical 10012592 Lacosamide ≥98% 50mg $306 2026-04-30 Buy
DC Chemicals DC8797 Lacosamide >98% 250mg $400 2026-05-24 Buy
DC Chemicals DC8797 Lacosamide >98% 1g $800 2026-05-24 Buy
DC Chemicals DC8797 Lacosamide >98% 100mg $200 2021-12-16 Buy
DC Chemicals DC8797 Lacosamide >98% 100mg $200 2026-05-24 Buy
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Properties

Melting point :141-143C
alpha :D23 +16.0° (c = 1 in CH3OH)
Boiling point :536.4±50.0 °C(Predicted)
Density :1.120±0.06 g/cm3(Predicted)
Flash point :2℃
storage temp. :Refrigerator
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml
pka :14.19±0.46(Predicted)
form :A crystalline solid
color :white to beige
optical activity :[α]/D 13 to 18° (C=0.5g/100mL, MeOH)
InChI :InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
InChIKey :VPPJLAIAVCUEMN-GFCCVEGCSA-N
SMILES :C(NCC1=CC=CC=C1)(=O)[C@H](NC(C)=O)COC
CAS DataBase Reference :175481-36-4

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lacosamide (LCM), (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037) is a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsant or antiepileptic drug. It reduces the spread of seizure activity in the brain. Lacosamide appears to have a dual mode of action: selective enhancement of sodium channel inactivation and modulation of collapsin response mediator protein-2.  Compared to novel antiepileptic drugs, lacosamide has broader and higher efficacy, better tolerability, and improved pharmacokinetic properties. Lacosamide is in phase III clinical development for adjunctive treatment of patients with uncontrolled partial-onset seizures, and for monotherapy of patients with painful diabetic neuropathy. It is absorbed rapidly and completely after oral administration. Lacosamide has an elimination half-life of approximately 13 hours and a low potential for drug interactions. Additionally, lacosamide exhibits linear, dose-proportional pharmacokinetics with low intra- and interpatient variability.

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Suppliers and manufacturers

Hebei Yanxi Chemical Co., Ltd.
LACOSAMIDE
$1.00 /1000kg
LACOSAMIDE CAS:175481-36-4
Changzhou Rokechem Technology Co., Ltd.
Lacosamide
$0.00 /1Kg
Lacosamide CAS:175481-36-4
Zibo Hangyu Biotechnology Development Co., Ltd
LACOSAMIDE
$10.00 /1KG
LACOSAMIDE CAS:175481-36-4
Chongqing Soarwin Technology Co., Ltd
Lacosamide
$0.00 /1kg
Lacosamide CAS:175481-36-4
Beijing Hope Pharmaceutical Co., Ltd.
Capot Chemical Co.,Ltd.
Nanjing Gold Pharmaceutical Technology Co. Ltd.
Henan Tianfu Chemical Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED