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ChemicalBook >> CAS DataBase List >> LM 22A4

LM 22A4

LM 22A4 price.
  • $19 - $2120
  • Product name: LM 22A4
  • CAS: 37988-18-4
  • MF: C15H21N3O6
  • MW: 339.34
  • EINECS:-0
  • MDL Number:MFCD00382831
  • Synonyms:LM 22A4;N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide;1-N,3-N,5-N-TRIS(2-HYDROXYETHYL)BENZENE-1,3,5-TRICARBOXAMIDE;BD2-4;N,N',N''-Tris(beta-hydroxyethyl)trimesamide;LM 22A4; LM 22A-4;1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(2-hydroxyethyl)-;LM-22A-4,Inhibitor,Trk Receptor,inhibit,LM22A4,LM22A-4,Tropomyosin related kinase receptor,LM22A 4
69 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Acints
  • Advanced Chemicals Intermediat
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Azepine
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 1mg
  • 25
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1mlx10mM(inDMSO)
  • 1G
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99
  • Packaging5mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99%
  • Packaging1mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99
  • Packaging10mg
  • Price$75
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99
  • Packaging25mg
  • Price$142
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99
  • Packaging50mg
  • Price$231
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA00C9MT
  • Product descriptionN1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99
  • Packaging100mg
  • Price$384
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10663
  • Product descriptionLM 22A4 98%
  • Packaging1G
  • Price$1200
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10663
  • Product descriptionLM 22A4 98%
  • Packaging100MG
  • Price$200
  • Updated2026-05-27
  • Buy
  • ManufacturerAcints
  • Product numberATI-06I-001
  • Product descriptionBenzene-1,3,5-tricarboxylic acid tris-[(2-hydroxy-ethyl)-amide] Notavailable
  • Packaging100mg
  • Price$553.5
  • Updated2026-05-20
  • Buy
  • ManufacturerAdvanced Chemicals Intermediat
  • Product numberATI-06I-001
  • Product descriptionBenzene-1,3,5-tricarboxylic acid tris-[(2-hydroxy-ethyl)-amide] Notavailable
  • Packaging100mg
  • Price$553.5
  • Updated2026-05-19
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5049
  • Product descriptionLM22A-4
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM22A4
  • Packaging25mg
  • Price$394
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM 22A4
  • Packaging25mg
  • Price$291
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM 22A4
  • Packaging100mg
  • Price$760
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM 22A4
  • Packaging50mg
  • Price$508
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5655
  • Product descriptionLM 22A4
  • Packaging10mg
  • Price$142
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99 5mg $52 2026-05-28 Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99% 1mg $19 2026-05-28 Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99 10mg $75 2026-05-28 Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99 25mg $142 2026-05-28 Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99 50mg $231 2026-05-28 Buy
aablocks AA00C9MT N1,N3,N5-Tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide 99 100mg $384 2026-05-28 Buy
ACHEMBLOCK 10663 LM 22A4 98% 1G $1200 2026-05-27 Buy
ACHEMBLOCK 10663 LM 22A4 98% 100MG $200 2026-05-27 Buy
Acints ATI-06I-001 Benzene-1,3,5-tricarboxylic acid tris-[(2-hydroxy-ethyl)-amide] Notavailable 100mg $553.5 2026-05-20 Buy
Advanced Chemicals Intermediat ATI-06I-001 Benzene-1,3,5-tricarboxylic acid tris-[(2-hydroxy-ethyl)-amide] Notavailable 100mg $553.5 2026-05-19 Buy
AK Scientific SYN5049 LM22A-4 50mg $470 2021-12-16 Buy
ApexBio Technology B5655 LM22A4 25mg $394 2021-12-16 Buy
ApexBio Technology B5655 LM 22A4 25mg $291 2026-05-06 Buy
ApexBio Technology B5655 LM 22A4 100mg $760 2026-05-06 Buy
ApexBio Technology B5655 LM 22A4 50mg $508 2026-05-06 Buy
ApexBio Technology B5655 LM 22A4 10mg $142 2026-05-06 Buy

Properties

storage temp. :2-8°C
solubility :H2O: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige
Water Solubility :H2O: 2mg/mL, clear (warmed)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChI :1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)
InChIKey :RGWJKANXFYJKHN-UHFFFAOYSA-N
SMILES :N(CCO)C(=O)c1cc(cc(c1)C(=O)NCCO)C(=O)NCCO

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

LM22A-4 (37988-18-4) is a small molecule BDNF mimetic displaying neurotrophhic activity. Partial agonist at TRKB and activates TRKB signaling. In in vitro models of neurodegenerative disease, it prevented neuronal degeneration with equal efficacy to that of BDNF. After in vivo administraton, LM22A-4 caused hippocampal and striatal TrkB activation in mice and improved motor learning after traumatic brain injury in rats.1Improves respiratory function in a mouse models of Rett syndrome.2

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