Loperamide hydrochloride
|
- $20 - $1045
- Product name: Loperamide hydrochloride
- CAS: 34552-83-5
- MF: C29H34Cl2N2O2
- MW: 513.5
- EINECS:252-082-4
- MDL Number:MFCD00058581
- Synonyms:4-(p-chlorophenyl)-4-hydroxy-n,n-dimethyl-alpha,alpha-diphenyl-1-piperidine ;blox ;butyramidehcl ;dissenten ;fortasec ;imodium ;imosec ;LABOTEST-BB LT00134703
39 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Aronis compounds
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 500mg
- 1g
- 5G
- 10g
- 25g
- l0750000
- 100g
- 250g
- 50 mg
- ManufacturerAHH
- Product numberAPI-1804
- Product descriptionLoperamide hydrochloride 98%
- Packaging250g
- Price$520
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10566
- Product descriptionLoperamide hydrochloride
- Packaging1g
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95110
- Product descriptionLoperamide hydrochloride
- Packaging25g
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAronis compounds
- Product numbere00898
- Product description4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-N,N-dimethyl-2,2-diphenylbutanamidehydrochloride
- Packaging10mg
- Price$20
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBL166178
- Product descriptionLoperamide hydrochloride
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging5mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging5mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging10mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging10mg
- Price$55
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging25mg
- Price$77
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging25mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging50mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14875
- Product descriptionLoperamide (hydrochloride) ≥98%
- Packaging50mg
- Price$120
- Updated2026-04-30
- Buy
- ManufacturerChemenu
- Product numberCM110528
- Product descriptionLoperamide hydrochloride 97%
- Packaging25g
- Price$143
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number37987
- Product descriptionLoperamidehydrochloride,98%(HPLC) 98%(HPLC)
- Packaging25G
- Price$256.48
- Updated2021-12-16
- Buy
- ManufacturerChem-Impex
- Product number37987
- Product descriptionLoperamidehydrochloride,98%(HPLC) 98%(HPLC)
- Packaging5G
- Price$73.92
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | API-1804 | Loperamide hydrochloride 98% | 250g | $520 | 2021-12-16 | Buy |
| AK Scientific | J10566 | Loperamide hydrochloride | 1g | $76 | 2021-12-16 | Buy |
| AK Scientific | J95110 | Loperamide hydrochloride | 25g | $140 | 2021-12-16 | Buy |
| Aronis compounds | e00898 | 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-N,N-dimethyl-2,2-diphenylbutanamidehydrochloride | 10mg | $20 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BL166178 | Loperamide hydrochloride | 100mg | $50 | 2021-12-16 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 5mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 10mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 10mg | $55 | 2026-04-30 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 25mg | $77 | 2026-04-30 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 25mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 50mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 14875 | Loperamide (hydrochloride) ≥98% | 50mg | $120 | 2026-04-30 | Buy |
| Chemenu | CM110528 | Loperamide hydrochloride 97% | 25g | $143 | 2021-12-16 | Buy |
| Chem-Impex | 37987 | Loperamidehydrochloride,98%(HPLC) 98%(HPLC) | 25G | $256.48 | 2021-12-16 | Buy |
| Chem-Impex | 37987 | Loperamidehydrochloride,98%(HPLC) 98%(HPLC) | 5G | $73.92 | 2021-12-16 | Buy |
Properties
Melting point :223-225°C
Density :1.1905 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
pka :8.66(at 25℃)
form :Solid
color :White to Almost white
Merck :14,5571
Major Application :forensics and toxicology
pharmaceutical (small molecule) InChI :InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
InChIKey :PGYPOBZJRVSMDS-UHFFFAOYSA-N
SMILES :C(C(=O)N(C)C)(CCN1CCC(O)(C2C=CC(Cl)=CC=2)CC1)(C1=CC=CC=C1)C1=CC=CC=C1.Cl
CAS DataBase Reference :34552-83-5(CAS DataBase Reference)
Density :1.1905 (rough estimate)
refractive index :1.6100 (estimate)
storage temp. :2-8°C
solubility :Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methanol.
pka :8.66(at 25℃)
form :Solid
color :White to Almost white
Merck :14,5571
Major Application :forensics and toxicology
pharmaceutical (small molecule) InChI :InChI=1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
InChIKey :PGYPOBZJRVSMDS-UHFFFAOYSA-N
SMILES :C(C(=O)N(C)C)(CCN1CCC(O)(C2C=CC(Cl)=CC=2)CC1)(C1=CC=CC=C1)C1=CC=CC=C1.Cl
CAS DataBase Reference :34552-83-5(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. Loperamide is an opiate which potently and selectively activates μ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. It is a much weaker agonist of the δ opiod receptor (Ki = 50 nM). Through its actions in the gut wall, loperamide has antidiarrheal action by increasing transit time and by altering intestinal transport of water and electrolytes. It also blocks voltage-sensitive sodium channels (IC50 = 270 nM) and high voltage-activated calcium channels (IC50 = 900 nM), presumably through an inhibitory effect on calmodulin. Loperamide is comparable to morphine in blocking peripheral pain in rats.More related product prices
Diphenylsilane Dimethyl ether Xylene Topotecan hydrochloride Dimethyl phthalate Dimethyl sulfate Dimethyl carbonate ETHANE Dacthal tert-Butylchlorodiphenylsilane Diphenyldiethoxysilane Dichlorodiphenylsilane Dimethyl fumarate Chlorodiphenylphosphine Dimethyl sulfoxide N,N-Dimethylformamide Diphenylphosphine Rimantadine 111-51-3Related product price
- Diphenylsilane
$10-700 - Dimethyl ether
$75-649 - Xylene
$9-6709.97
Suppliers and manufacturers
APOLLO HEALTHCARE RESOURCES
