METHYSERGIDE MALEATE
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- $36 - $2166
- Product name: METHYSERGIDE MALEATE
- CAS: 129-49-7
- MF: C21H27N3O2.C4H4O4
- MW: 469.53
- EINECS:204-950-9
- MDL Number:MFCD00083185
- Synonyms:1-(hydroxymethyl)propylamideof1-methyl-(+)-lysergicacidhydrogenmaleate ;deseril-retard ;ergoline-8-beta-carboxamide,9,10-didehydro-n-(1-(hydroxymethyl)propyl)-1,6-dim ;maleate(1:1)(salt) ;Methysergide Maleate, USP;Methysergide Maleate (350 mg);LWYXFDXUMVEZKS-ZVFOLQIPSA-N;methysergidebimaleate
45 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth
- Cayman Chemical
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 10
- 50MG
- 100mg
- 350mg
- Manufactureraablocks
- Product numberAA01CCFN
- Product description1-Methyl-D-lysergic acid butanolamide bimaleate ≥95%
- Packaging1mg
- Price$36
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CCFN
- Product description1-Methyl-D-lysergic acid butanolamide bimaleate ≥95%
- Packaging5mg
- Price$120
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CCFN
- Product description1-Methyl-D-lysergic acid butanolamide bimaleate ≥95%
- Packaging10mg
- Price$186
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA01CCFN
- Product description1-Methyl-D-lysergic acid butanolamide bimaleate ≥95%
- Packaging25mg
- Price$420
- Updated2026-05-29
- Buy
- ManufacturerAK Scientific
- Product numberG831
- Product descriptionMethysergide maleate
- Packaging25mg
- Price$522
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002261
- Product descriptionDESERIL 95.00%
- Packaging10MG
- Price$726.44
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0002261
- Product descriptionDESERIL 95.00%
- Packaging50MG
- Price$1352.22
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging50mg
- Price$1385
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging25mg
- Price$525
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging10mg
- Price$235
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging5mg
- Price$150
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB5046
- Product descriptionMethysergide maleate
- Packaging1mg
- Price$50
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFM39378
- Product descriptionMethysergide maleate monohydrate
- Packaging1mg
- Price$150
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFM39378
- Product descriptionMethysergide maleate monohydrate
- Packaging2mg
- Price$177.8
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFM75152
- Product descriptionMethysergide maleate
- Packaging10mg
- Price$571.1
- Updated2026-06-04
- Buy
- ManufacturerBiosynth
- Product numberFM75152
- Product descriptionMethysergide maleate
- Packaging25mg
- Price$714
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01CCFN | 1-Methyl-D-lysergic acid butanolamide bimaleate ≥95% | 1mg | $36 | 2026-05-29 | Buy |
| aablocks | AA01CCFN | 1-Methyl-D-lysergic acid butanolamide bimaleate ≥95% | 5mg | $120 | 2026-05-29 | Buy |
| aablocks | AA01CCFN | 1-Methyl-D-lysergic acid butanolamide bimaleate ≥95% | 10mg | $186 | 2026-05-29 | Buy |
| aablocks | AA01CCFN | 1-Methyl-D-lysergic acid butanolamide bimaleate ≥95% | 25mg | $420 | 2026-05-29 | Buy |
| AK Scientific | G831 | Methysergide maleate | 25mg | $522 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002261 | DESERIL 95.00% | 10MG | $726.44 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0002261 | DESERIL 95.00% | 50MG | $1352.22 | 2021-12-16 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 50mg | $1385 | 2026-05-06 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 25mg | $525 | 2026-05-06 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 10mg | $235 | 2026-05-06 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 5mg | $150 | 2026-05-06 | Buy |
| ApexBio Technology | B5046 | Methysergide maleate | 1mg | $50 | 2026-05-06 | Buy |
| Biosynth | FM39378 | Methysergide maleate monohydrate | 1mg | $150 | 2026-06-04 | Buy |
| Biosynth | FM39378 | Methysergide maleate monohydrate | 2mg | $177.8 | 2026-06-04 | Buy |
| Biosynth | FM75152 | Methysergide maleate | 10mg | $571.1 | 2026-06-04 | Buy |
| Biosynth | FM75152 | Methysergide maleate | 25mg | $714 | 2026-06-04 | Buy |
Properties
storage temp. :Store at RT
solubility :DMSO: >10 mg/mL
form :solid
color :white to off-white
Water Solubility :Soluble to 10 mM in water with gentle warming
Stability :Hygroscopic
InChIKey :LWYXFDXUMVEZKS-ZVFOLQIPSA-N
SMILES :[n]1(c2c3c(c1)C[C@H]4N(C[C@@H](C=C4c3ccc2)C(=O)N[C@H](CO)CC)C)C.OC(=O)\C=C/C(=O)O
solubility :DMSO: >10 mg/mL
form :solid
color :white to off-white
Water Solubility :Soluble to 10 mM in water with gentle warming
Stability :Hygroscopic
InChIKey :LWYXFDXUMVEZKS-ZVFOLQIPSA-N
SMILES :[n]1(c2c3c(c1)C[C@H]4N(C[C@@H](C=C4c3ccc2)C(=O)N[C@H](CO)CC)C)C.OC(=O)\C=C/C(=O)O
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Methysergide is an agonist of the serotonin (5-HT) receptor subtype 5-HT1 and an antagonist of 5-HT2 receptors. It binds to recombinant human 5-HT1A (KD = 23.44 nM), 5-HT1E (Ki = 229.09 nM), 5-HT1F (Ki = 33.88 nM), and rodent 5-HT1B receptors (KD = 1,513.56 nM). It also binds to recombinant human 5-HT2A (Ki = 2.69 nM) and 5-HT2C receptors (KD = 1.26 nM) and is an insurmountable antagonist at 5-HT2B receptors. It inhibits vasoconstriction induced by 5-HT in isolated postmortem human basilar arterial spiral strips (pA2 = 8.07). Methysergide decreases external carotid blood flow in a dose-dependent manner in vagosympathectomized dogs, an effect that is inhibited by the 5-HT1B/1D receptor antagonist GR127935 . It has antinociceptive activity in mouse models of pain induced by intrathecal injection of substance P , glutamate, NMDA , AMPA , or kainic acid. Methysergide reduces zymosan-induced paw edema in rats when administered at a dose of 10 mg/kg. Formulations containing methysergide were previously used in the prevention and treatment of vascular headaches.Related product price
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Suppliers and manufacturers
3B Pharmachem (Wuhan) International Co.,Ltd.
LGM Pharma
Spectrum Chemical Manufacturing Corp.
BOC Sciences
Shanghai TaoSu Biochemical Technology Co., Ltd.
Chizhou Kailong Import and Export Trade Co., Ltd.
Sigma-Aldrich
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.