Mitomycin C
|
- $53 - $4570.68
- Product name: Mitomycin C
- CAS: 50-07-7
- MF: C15H18N4O5
- MW: 334.33
- EINECS:200-008-6
- MDL Number:MFCD00078109
- Synonyms:Mitomycin C(Ametycine);Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-;Mytomycin C;[1aR-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-α]indole-4,7-dione;6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methox-5-methylazirino[2',3':3,4]pyrrolo[1,2-;MitonyycinC;[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;8balpha)]-8aalph
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Brand
- ACHEMBLOCK
- Adipogen Life Sciences
- AHH
- AK Scientific
- ApexBio Technology
- Apolloscientific
- AvaChem
- Biosynth
- BroadPharm
- Cayman Chemical
- Chem-Impex
- DC Chemicals
- Sigma-Aldrich
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Package
- 10mM*1mLinDMSO
- 2mg
- 4mg
- 5mg
- 10mg
- 5x2mg
- 12mg
- 10x2mg
- 24mg
- 25mg
- 40mg
- 50x2mg
- 10
- 50mg
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- 0.1g
- 0.25g
- 250mg
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- 0.5g
- 1ml
- 1G
- 1000mg
- 2g
- 25G
- 10mM(in 1mL DMSO)
- 250G
- 70 mg
- 10mM(in1mLDMSO)
- ManufacturerACHEMBLOCK
- Product number10408
- Product descriptionMitomycin C 98%
- Packaging100MG
- Price$450
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10408
- Product descriptionMitomycin C 98%
- Packaging1G
- Price$1050
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0161-M005
- Product descriptionMitomycin C
- Packaging5mg
- Price$53
- Updated2026-05-06
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- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0161-M010
- Product descriptionMitomycin C
- Packaging10mg
- Price$93
- Updated2026-05-06
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- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0161-M025
- Product descriptionMitomycin C
- Packaging25mg
- Price$171
- Updated2026-05-06
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- ManufacturerAHH
- Product numberMT-54310
- Product descriptionMitomycin 97%
- Packaging0.1g
- Price$310
- Updated2026-05-26
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- ManufacturerAK Scientific
- Product numberC474
- Product descriptionMitomycin C 98%(HPLC)
- Packaging25mg
- Price$397
- Updated2026-06-04
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- ManufacturerAK Scientific
- Product numberC474
- Product descriptionMitomycin C 98%(HPLC)
- Packaging50mg
- Price$597
- Updated2026-06-04
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- ManufacturerAK Scientific
- Product numberC474
- Product descriptionMitomycin C 98%(HPLC)
- Packaging10mg
- Price$206
- Updated2026-06-04
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- ManufacturerAK Scientific
- Product numberC474
- Product descriptionMitomycin C 98%(HPLC)
- Packaging5mg
- Price$146
- Updated2026-06-04
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- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging5mg
- Price$55
- Updated2026-05-06
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- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging10mM(in 1mL DMSO)
- Price$58
- Updated2021-12-16
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- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
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- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging10mg
- Price$77
- Updated2026-05-06
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- ManufacturerApolloscientific
- Product numberBIM0133
- Product descriptionMitomycin C
- Packaging10mg
- Price$85
- Updated2026-06-04
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- ManufacturerApolloscientific
- Product numberBIM0133
- Product descriptionMitomycin C
- Packaging5mg
- Price$66
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | 10408 | Mitomycin C 98% | 100MG | $450 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10408 | Mitomycin C 98% | 1G | $1050 | 2026-05-27 | Buy |
| Adipogen Life Sciences | CDX-M0161-M005 | Mitomycin C | 5mg | $53 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-M0161-M010 | Mitomycin C | 10mg | $93 | 2026-05-06 | Buy |
| Adipogen Life Sciences | CDX-M0161-M025 | Mitomycin C | 25mg | $171 | 2026-05-06 | Buy |
| AHH | MT-54310 | Mitomycin 97% | 0.1g | $310 | 2026-05-26 | Buy |
| AK Scientific | C474 | Mitomycin C 98%(HPLC) | 25mg | $397 | 2026-06-04 | Buy |
| AK Scientific | C474 | Mitomycin C 98%(HPLC) | 50mg | $597 | 2026-06-04 | Buy |
| AK Scientific | C474 | Mitomycin C 98%(HPLC) | 10mg | $206 | 2026-06-04 | Buy |
| AK Scientific | C474 | Mitomycin C 98%(HPLC) | 5mg | $146 | 2026-06-04 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 10mM(in 1mL DMSO) | $58 | 2021-12-16 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 10mg | $77 | 2026-05-06 | Buy |
| Apolloscientific | BIM0133 | Mitomycin C | 10mg | $85 | 2026-06-04 | Buy |
| Apolloscientific | BIM0133 | Mitomycin C | 5mg | $66 | 2021-12-16 | Buy |
Properties
Melting point :360 °C
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0~7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
InChI :1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChIKey :NWIBSHFKIJFRCO-WUDYKRTCSA-N
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0~7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
InChI :1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChIKey :NWIBSHFKIJFRCO-WUDYKRTCSA-N
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Safety Information
| Symbol(GHS): |
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Description
Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.Although it is active against a wide variety of tumors, newer agents have largely replaced MMC except in anal cancer; outside of the United States, MMC is infrequently used for treatment of advanced non-small cell lung cancer (NSCLC), and breast cancer.
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