PD158780
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- $41 - $1800
- Product name: PD158780
- CAS: 171179-06-9
- MF: C14H12BrN5
- MW: 330.18
- EINECS:
- MDL Number:MFCD00942160
- Synonyms:N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine;Pyrido[3,4-d]pyriMidine-4,6-diaMine,N4-(3-broMophenyl)-N6-Methyl- (Related Reference);Pyrido[3,4-d]pyriMidine-4,6-diaMine,N4-(3-broMophenyl)-N6-Methyl-;PD 158780 solution;InSolution? PD 158780 ;PD 158780 - CAS 171179-06-9 - Calbiochem;InSolution PD 158780 - CAS 171179-06-9 - Calbiochem;PD 158780; PD-158780
49 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 250mg
- 1g
- 10mM*1mLinDMSO(Solid+Solvent)
- 500μg
- 1000μg
- 10mM*1mLinDMSO
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine ≥98%
- Packaging1mg
- Price$41
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging5mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging10mg
- Price$118
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging25mg
- Price$203
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging50mg
- Price$338
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003SLA
- Product descriptionN4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging100mg
- Price$486
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228490
- Product descriptionPD158780 97.00%
- Packaging25MG
- Price$270
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228490
- Product descriptionPD158780 97.00%
- Packaging100MG
- Price$695
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number3959AH
- Product description4-N-(3-Bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine
- Packaging50mg
- Price$543
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA360151
- Product descriptionPD 158780 98+%
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA360151
- Product descriptionPD 158780 98+%
- Packaging10mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001327
- Product descriptionPD 158780 95.00%
- Packaging5MG
- Price$502.91
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001327
- Product descriptionPD 158780 95.00%
- Packaging1MG
- Price$140.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7130
- Product descriptionPD 158780
- Packaging50mg
- Price$504
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB7130
- Product descriptionPD 158780
- Packaging10mg
- Price$152
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-18609
- Product descriptionPD158780 99.47%
- Packaging10mg
- Price$143
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine ≥98% | 1mg | $41 | 2026-05-28 | Buy |
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 5mg | $82 | 2026-05-28 | Buy |
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 10mg | $118 | 2026-05-28 | Buy |
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 25mg | $203 | 2026-05-28 | Buy |
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 50mg | $338 | 2026-05-28 | Buy |
| aablocks | AA003SLA | N4-(3-Bromophenyl)-N6-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 100mg | $486 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y228490 | PD158780 97.00% | 25MG | $270 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228490 | PD158780 97.00% | 100MG | $695 | 2026-05-27 | Buy |
| AK Scientific | 3959AH | 4-N-(3-Bromophenyl)-6-N-methylpyrido[3,4-d]pyrimidine-4,6-diamine | 50mg | $543 | 2021-12-16 | Buy |
| Ambeed | A360151 | PD 158780 98+% | 5mg | $65 | 2021-12-16 | Buy |
| Ambeed | A360151 | PD 158780 98+% | 10mg | $97 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001327 | PD 158780 95.00% | 5MG | $502.91 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001327 | PD 158780 95.00% | 1MG | $140.7 | 2021-12-16 | Buy |
| ApexBio Technology | B7130 | PD 158780 | 50mg | $504 | 2026-05-06 | Buy |
| ApexBio Technology | B7130 | PD 158780 | 10mg | $152 | 2026-05-06 | Buy |
| Arctom | HY-18609 | PD158780 99.47% | 10mg | $143 | 2026-05-26 | Buy |
Properties
Melting point :174.0 to 178.0 °C
Boiling point :499.6±45.0 °C(Predicted)
Density :1.611±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: ≥20mg/mL
form :Yellow solid
pka :5.80±0.30(Predicted)
color :yellow
InChI :1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
InChIKey :KFHMLBXBRCITHF-UHFFFAOYSA-N
Boiling point :499.6±45.0 °C(Predicted)
Density :1.611±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO: ≥20mg/mL
form :Yellow solid
pka :5.80±0.30(Predicted)
color :yellow
InChI :1S/C14H12BrN5/c1-16-13-6-11-12(7-17-13)18-8-19-14(11)20-10-4-2-3-9(15)5-10/h2-8H,1H3,(H,16,17)(H,18,19,20)
InChIKey :KFHMLBXBRCITHF-UHFFFAOYSA-N
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
PD 158780 is a pyridopyrimidine derivative that reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor tyrosine kinase superfamily: EGFR (IC50 = 8 μM), ErbB2 (IC50 = 49 nM), ErbB3, and ErbB4 (IC50 = 52 nM). It does not inhibit PDGF or FGF-mediated tyrosine phosphorylation. At 0.5 μM, PD 158780 has been shown to induce G1 cell cycle arrest in MCF10A breast cancer cells.Related product price
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Pyridine
$9-54675 -
2-Phenylpyridine
$4-4125 -
2-Bromopyridine
$6-1383.74
