PF 04418948
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- $19 - $2200
- Product name: PF 04418948
- CAS: 1078166-57-0
- MF: C23H20FNO5
- MW: 409.41
- EINECS:
- MDL Number:MFCD24387541
- Synonyms:1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid;PF 04418948;1-(4-FLUOROBENZOYL)-3-[(6-METHOXYNAPHTHALEN-2-YL)OXYMETHYL]AZETIDINE-3-CARBOXYLIC ACID;PF-04418948;PF04418948;PF 04418948;CS-2852;PF-0441848;PF04418948; PF 04418948;3-Azetidinecarboxylic acid, 1-(4-fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-
50 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 1mg
- 5mg
- 10mM*1mLinDMSO(Solution)
- 10mg
- 50
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 100mg
- 250mg
- 1g
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging5mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging10mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging25mg
- Price$110
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging50mg
- Price$173
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging100mg
- Price$272
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA008TK4
- Product descriptionPF-04418948 98+%
- Packaging250mg
- Price$463
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65614
- Product description1-(4-fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylic acid 98%
- Packaging100MG
- Price$335
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberQ65614
- Product description1-(4-fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylic acid 98%
- Packaging25MG
- Price$115
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2831DC
- Product descriptionPF-04418948
- Packaging10mg
- Price$262
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging50mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging25mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging5mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging100mg
- Price$353
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA920639
- Product description1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+%
- Packaging250mg
- Price$705
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA008TK4 | PF-04418948 98+% | 1mg | $19 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 5mg | $34 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 10mg | $55 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 25mg | $110 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 50mg | $173 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 100mg | $272 | 2026-05-28 | Buy |
| aablocks | AA008TK4 | PF-04418948 98+% | 250mg | $463 | 2026-05-28 | Buy |
| ACHEMBLOCK | Q65614 | 1-(4-fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylic acid 98% | 100MG | $335 | 2026-05-27 | Buy |
| ACHEMBLOCK | Q65614 | 1-(4-fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylic acid 98% | 25MG | $115 | 2026-05-27 | Buy |
| AK Scientific | 2831DC | PF-04418948 | 10mg | $262 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 50mg | $272 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 25mg | $158 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 5mg | $48 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 10mg | $75 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 100mg | $353 | 2021-12-16 | Buy |
| Ambeed | A920639 | 1-(4-Fluorobenzoyl)-3-(((6-methoxynaphthalen-2-yl)oxy)methyl)azetidine-3-carboxylicacid 98+% | 250mg | $705 | 2021-12-16 | Buy |
Properties
Melting point :171-172°C
Boiling point :639.1±55.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.25±0.20(Predicted)
color :white to beige
InChI :InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChIKey :POJZIZBONPAWIV-UHFFFAOYSA-N
SMILES :N1(C(=O)C2=CC=C(F)C=C2)CC(COC2=CC=C3C(=C2)C=CC(OC)=C3)(C(O)=O)C1
Boiling point :639.1±55.0 °C(Predicted)
Density :1.357±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble20mg/mL, clear
form :powder
pka :3.25±0.20(Predicted)
color :white to beige
InChI :InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)
InChIKey :POJZIZBONPAWIV-UHFFFAOYSA-N
SMILES :N1(C(=O)C2=CC=C(F)C=C2)CC(COC2=CC=C3C(=C2)C=CC(OC)=C3)(C(O)=O)C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Prostaglandin E2 (PGE2) evokes distinct responses through four different ‘E prostanoid’ (EP) receptors. EP2 is a G protein-coupled receptor which signals preferentially through Gs proteins. PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM). It is over a thousand-fold less active at other prostanoid receptors, including other EP receptors. PF-04418948 can be used in cells and tissues. In rats, it significantly reduces the effects of the EP2-selective agonist butaprost on cutaneous blood flow when given orally.More related product prices
PF-06463922 3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione Dacomitinib (PF299804) PF-04971729 Oclacitinib PF-06447475Related product price
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PF-06463922
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3-(5-fluoro-indol-3-yl)-pyrrolidine-2,5-dione
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Dacomitinib (PF299804)
$10-1703
Suppliers and manufacturers
Shanghai Xuerong Chemical Technology Co., LTD
Chemsky（shanghai）International Co.,Ltd.
Haoyuan Chemexpress Co., Ltd.
MedChemexpress LLC
Shanghai Synmedia Chemical Co., Ltd.
Bide Pharmatech Ltd.
Mashilabs (Shanghai) Co.,Ltd.
AdooQ Bioscience CHINA
Sigma-Aldrich
Shanghai Lollane Biological Technology Co.,Ltd.