PIK-75 Hydrochloride
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- $17 - $1200
- Product name: PIK-75 Hydrochloride
- CAS: 372196-77-5
- MF: C16H14BrN5O4S.ClH
- MW: 488.74
- EINECS:
- MDL Number:MFCD12546130
- Synonyms:2-Methyl-5-nitrobenzenesulfonic acid [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide hydrochloride;PFK-15;(E)-N'-((6-bromoH-imidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide hydrochloride;2-Methyl-5-nitrobenzenesulfonic acid [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide hydrochloride PIK-75;Benzenesulfonic acid, 2-methyl-5-nitro-, 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide, hydrochloride (1:1);PIK-75;PIK 75;(E)-N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydraz;PIK-75 HCl
63 prices
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Brand
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
Package
- 1mg
- 5mg
- 20mg
- 250.00mg
- 50.00mg
- 100.00mg
- 50
- 10mM(in 1mL DMSO)
- 10mg
- 25mg
- 50mg
- 100MG
- 250MG
- 1g
- 10mM(in1mLDMSO)
- ManufacturerACHEMBLOCK
- Product numberX212430
- Product descriptionPIK-75 hydrochloride 97%
- Packaging100MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX212430
- Product descriptionPIK-75 hydrochloride 97%
- Packaging250MG
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5572
- Product descriptionPIK-75
- Packaging100mg
- Price$688
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging1g
- Price$1033
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging250mg
- Price$435
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging100mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging50mg
- Price$107
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA111266
- Product descriptionN'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+%
- Packaging25mg
- Price$67
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0041967
- Product descriptionN'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00%
- Packaging25MG
- Price$679.37
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0041967
- Product descriptionN'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00%
- Packaging50MG
- Price$721.57
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0041967
- Product descriptionN'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00%
- Packaging100MG
- Price$795.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2080
- Product descriptionPIK-75 HCl
- Packaging100mg
- Price$198
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2080
- Product descriptionPIK-75 HCl
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2080
- Product descriptionPIK-75 HCl
- Packaging10mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA2080
- Product descriptionPIK-75
- Packaging10mM(in 1mL DMSO)
- Price$61
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | X212430 | PIK-75 hydrochloride 97% | 100MG | $145 | 2026-05-27 | Buy |
| ACHEMBLOCK | X212430 | PIK-75 hydrochloride 97% | 250MG | $250 | 2026-05-27 | Buy |
| AK Scientific | SYN5572 | PIK-75 | 100mg | $688 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 1g | $1033 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 250mg | $435 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 100mg | $191 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 50mg | $107 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 10mg | $42 | 2021-12-16 | Buy |
| Ambeed | A111266 | N'-((6-Bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazidehydrochloride 99+% | 25mg | $67 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0041967 | N'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00% | 25MG | $679.37 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0041967 | N'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00% | 50MG | $721.57 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0041967 | N'-[(1E)-(6-BROMOIMIDAZO[1,2-A]PYRIDIN-3-YL)METHYLENE]-N,2-DIMETHYL-5-NITROBENZENESULFONOHYDRAZIDE HYDROCHLORIDE 95.00% | 100MG | $795.8 | 2021-12-16 | Buy |
| ApexBio Technology | A2080 | PIK-75 HCl | 100mg | $198 | 2026-05-06 | Buy |
| ApexBio Technology | A2080 | PIK-75 HCl | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | A2080 | PIK-75 HCl | 10mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | A2080 | PIK-75 | 10mM(in 1mL DMSO) | $61 | 2021-12-16 | Buy |
Properties
Melting point :>156°C (dec.)
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Light Beige to Beige
InChI :1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
InChIKey :VOUDEIAYNKZQKM-MYHMWQFYSA-N
SMILES :[S](=O)(=O)(N(\N=C\c2[n]3c(nc2)ccc(c3)Br)C)c1c(ccc(c1)[N+](=O)[O-])C.Cl
storage temp. :Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Light Beige to Beige
InChI :1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+;
InChIKey :VOUDEIAYNKZQKM-MYHMWQFYSA-N
SMILES :[S](=O)(=O)(N(\N=C\c2[n]3c(nc2)ccc(c3)Br)C)c1c(ccc(c1)[N+](=O)[O-])C.Cl
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
PIK-75 blocks production of PIP2 and/or PIP3, phosphorylation of Akt, and activation of mTORC1 in adipocytes and myotubes. PI 3-kinase (PI3K) catalyzes the synthesis of the second messengers PtdIns-(3)-P, PtdIns-(3,4)-P2, and PtdIns-(3,4,5)-P3. The PI 3-kinase family of enzymes is comprised of 15 members that are divided into three classes according to their structure, substrate specificity, and mode of regulation. In the class I PI 3-kinases, p110α is the primary PI 3-kinase isoform required for insulin signaling in adipocytes and myotubes and is frequently mutated in primary tumors. Small molecule inhibitors of p110α are of interest in cancer treatment research. PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM. PIK-75 inhibits p110γ and p110β considerably less effectively.More related product prices
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Suppliers and manufacturers
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