PX-866
|
- $60 - $4184
- Product name: PX-866
- CAS: 502632-66-8
- MF: C29H35NO8
- MW: 525.59
- EINECS:
- MDL Number:MFCD11840616
- Synonyms:PX-866 (Sonolisib);DJM-166;DJM-2-166;PX866;PX 866;DJM-166;DJM-2-166;(1E,4S,4aR,5R,6aS,9aR)-5-(Acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione;(2R,3S,6Z,11R,15S,17R)-6-{[bis(prop-2-en-1-yl)aMino]Methylidene}-8-hydroxy-3-(MethoxyMethyl)-2,15-diMethyl-5,9,14-trioxo-4-oxatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(10),7-dien-17-yl acetate;Sonolisib;(2R,3S,6Z,11R,15S,17R)-6-{[bis(prop-2-en-1-yl)aMino]Methylidene}-8-hydroxy-3-(MethoxyMethyl)-2,15-diMethyl-5,9,14-trioxo-4-oxatetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(10),7-dien-17-yl
28 prices
Selected condition：
Brand
- aablocks
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- Manufactureraablocks
- Product numberAA00DA8M
- Product descriptionPX-866 ≥95%
- Packaging1mg
- Price$81
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DA8M
- Product descriptionPX-866 ≥95%
- Packaging5mg
- Price$337
- Updated2026-05-28
- Buy
- ManufacturerApexBio Technology
- Product numberC3271
- Product descriptionPX 866
- Packaging1mg
- Price$137
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3271
- Product descriptionPX 866
- Packaging5mg
- Price$495
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC3271
- Product descriptionPX 866
- Packaging10mg
- Price$790
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging10mg
- Price$262
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging5mg
- Price$145
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging25mg
- Price$576
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging50mg
- Price$1045
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging100mg
- Price$1894
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIP1009
- Product descriptionPX-866
- Packaging250mg
- Price$4184
- Updated2026-06-04
- Buy
- ManufacturerArctom
- Product numberHY-N6775
- Product descriptionSonolisib 97.10%
- Packaging10mg
- Price$548
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-N6775
- Product descriptionSonolisib 97.10%
- Packaging5mg
- Price$342
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6713
- Product descriptionPX-866 98%
- Packaging1mg
- Price$60
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6713
- Product descriptionPX-866 98%
- Packaging5mg
- Price$240
- Updated2026-05-22
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545881
- Product descriptionPX-866 >98%
- Packaging5mg
- Price$299.2
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00DA8M | PX-866 ≥95% | 1mg | $81 | 2026-05-28 | Buy |
| aablocks | AA00DA8M | PX-866 ≥95% | 5mg | $337 | 2026-05-28 | Buy |
| ApexBio Technology | C3271 | PX 866 | 1mg | $137 | 2026-05-06 | Buy |
| ApexBio Technology | C3271 | PX 866 | 5mg | $495 | 2026-05-06 | Buy |
| ApexBio Technology | C3271 | PX 866 | 10mg | $790 | 2026-05-06 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 10mg | $262 | 2026-06-04 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 5mg | $145 | 2026-06-04 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 25mg | $576 | 2026-06-04 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 50mg | $1045 | 2026-06-04 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 100mg | $1894 | 2026-06-04 | Buy |
| Apolloscientific | BIP1009 | PX-866 | 250mg | $4184 | 2026-06-04 | Buy |
| Arctom | HY-N6775 | Sonolisib 97.10% | 10mg | $548 | 2026-05-26 | Buy |
| Arctom | HY-N6775 | Sonolisib 97.10% | 5mg | $342 | 2026-05-26 | Buy |
| AvaChem | 6713 | PX-866 98% | 1mg | $60 | 2026-05-22 | Buy |
| AvaChem | 6713 | PX-866 98% | 5mg | $240 | 2026-05-22 | Buy |
| Biorbyt Ltd | orb545881 | PX-866 >98% | 5mg | $299.2 | 2021-12-16 | Buy |
Properties
Boiling point :651.4±55.0 °C(Predicted)
Density :1.28
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :8.35±0.70(Predicted)
color :Orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
CAS DataBase Reference :502632-66-8
Density :1.28
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :8.35±0.70(Predicted)
color :Orange
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
CAS DataBase Reference :502632-66-8
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
PX 866 is a ring-opened analog of wortmannin that potently and irreversibly inhibits PI3K (IC50 = 0.1-88 nM). It less potently blocks the activity of mammalian target of rapamycin (mTOR, IC50 = 3.1 μM). PX 866 exhibits single agent in vivo anti-tumor activity and increases the anti-tumor effects of cisplatin and radiation treatment. In cancer cells grown in three-dimensional cultures, PX 866 reduces cell growth and motility without causing cytotoxicity. Consistent with having cytostatic effects, PX 866 dosing is associated with prolonged stable disease in cancer patients.Related product price
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