Pazopanib-d6
|
- $290 - $710
- Product name: Pazopanib-d6
- CAS: 1219592-01-4
- MF: C21H23N7O2S
- MW: 437.52
- EINECS:
- MDL Number:
- Synonyms:Pazopanib-d6;2-methyl-5-[[4-[methyl-d3-[3-methyl-2-(methyl-d3)-2H-indazol-6-yl]amino]-2-pyrimidinyl]amino]-benzenesulfonamide;2H6]-Pazopanib;2-methyl-5-({4-[(2H?)methyl[2-(2H?)methyl-3-methyl-2H-indazol-6-yl]amino]pyrimidin-2-yl}amino)benzene-1-sulfonamide;D6-Pazopanib
9 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
Package
- 500μg
- 1mg
- 500??g
- ManufacturerAK Scientific
- Product number3396DH
- Product description2-Methyl-5-[[4-[[3-methyl-2-(trideuteriomethyl)indazol-6-yl]-(trideuteriomethyl)amino]pyrimidin-2-yl]amino]benzenesulfonamide
- Packaging1mg
- Price$710
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number25446
- Product descriptionPazopanib-d6 ≥99%deuteratedforms(d1-d6)
- Packaging1mg
- Price$604
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number25446
- Product descriptionPazopanib-d6 ≥99% deuterated forms (d1-d6)
- Packaging500μg
- Price$290
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number25446
- Product descriptionPazopanib-d6 ≥99%deuteratedforms(d1-d6)
- Packaging500μg
- Price$319
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number25446
- Product descriptionPazopanib-d6 ≥99% deuterated forms (d1-d6)
- Packaging1mg
- Price$549
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0078393
- Product descriptionPazopanib-d6 98.0%
- Packaging1mg
- Price$574
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0078393
- Product descriptionPazopanib-d6 98.0%
- Packaging1mg
- Price$574
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0078393
- Product descriptionPazopanib-d6 98.0%
- Packaging500??g
- Price$303
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0078393
- Product descriptionPazopanib-d6 98.0%
- Packaging500??g
- Price$303
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3396DH | 2-Methyl-5-[[4-[[3-methyl-2-(trideuteriomethyl)indazol-6-yl]-(trideuteriomethyl)amino]pyrimidin-2-yl]amino]benzenesulfonamide | 1mg | $710 | 2021-12-16 | Buy |
| Cayman Chemical | 25446 | Pazopanib-d6 ≥99%deuteratedforms(d1-d6) | 1mg | $604 | 2026-04-30 | Buy |
| Cayman Chemical | 25446 | Pazopanib-d6 ≥99% deuterated forms (d1-d6) | 500μg | $290 | 2024-03-01 | Buy |
| Cayman Chemical | 25446 | Pazopanib-d6 ≥99%deuteratedforms(d1-d6) | 500μg | $319 | 2026-04-30 | Buy |
| Cayman Chemical | 25446 | Pazopanib-d6 ≥99% deuterated forms (d1-d6) | 1mg | $549 | 2024-03-01 | Buy |
| ChemScene | CS-0078393 | Pazopanib-d6 98.0% | 1mg | $574 | 2026-06-04 | Buy |
| ChemScene | CS-0078393 | Pazopanib-d6 98.0% | 1mg | $574 | 2026-06-04 | Buy |
| ChemScene | CS-0078393 | Pazopanib-d6 98.0% | 500??g | $303 | 2026-06-04 | Buy |
| ChemScene | CS-0078393 | Pazopanib-d6 98.0% | 500??g | $303 | 2026-06-04 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMSO: 16 mg/ml
form :A solid
color :White to off-white
solubility :DMF: 16 mg/ml; DMSO: 16 mg/ml
form :A solid
color :White to off-white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
Pazopanib-d6 is intended for use as an internal standard for the quantification of pazopanib by GC- or LC-MS. Pazopanib is a multi-kinase inhibitor that inhibits the VEGF receptors VEGFR1, VEGFR2, and VEGFR3 (IC50s = 10, 30, and 47 nM, respectively, in a cell-free enzyme assay).1 It also inhibits PDGFRα, PDGFRβ, and c-Kit (IC50s = 71, 84, and 74 nM, respectively, in a cell-free enzyme assay) as well as additional receptor tyrosine kinases. Pazopanib inhibits upregulation of the surface adhesion proteins ICAM-1 and VCAM-1 induced by VEGF in multiple myeloma cells cocultured with human umbilical vein endothelial cells (HUVECs) and decreases multiple myeloma cell adhesion to HUVECs.2 It also inhibits proliferation of multiple myeloma cells cocultured with HUVECs. Pazopanib (30 and 100 mg/kg) reduces tumor growth, induces apoptosis, decreases angiogenesis, and increases survival in a multiple myeloma mouse xenograft model. Formulations containing pazopanib have been used in the treatment of cancer.More related product prices
444731-75-3 N-(2-chloropyriMidin-4-yl)-2,3-diMethyl-2H- indazol-6-aMine 3-AMINO-4-METHYLBENZENESULFONAMIDE 1,3-DiMethyl-6-aMino-1H-indazole 5-[[4-[(2,3-DiMethyl-2H-indazol-6-yl)aMino]-2-pyriMidinyl]aMino]-2-MethylbenzenesulfonaMide 2-Methyl-5-nitrobenzenesulfonamide 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE Pazopanib 2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI) 4(1H)-Pyrimidinone, 2-chloro- (9CI) 2,3-dimethyl-2H-indazol-6-amine hydrochloride 3-Methyl-6-nitroindazole 20191-74-6 6973-09-7 3-Methyl-1H-indazol-6-ylamine ,97% 5-Amino-2,3-dimethyl-2H-indazole 2,4-Dichloropyrimidine 6-NitroindazoleRelated product price
-
444731-75-3
$12-8639.4 -
N-(2-chloropyriMidin-4-yl)-2,3-diMethyl-2H- indazol-6-aMine
$9-1824 -
3-AMINO-4-METHYLBENZENESULFONAMIDE
$50-2175
Suppliers and manufacturers
Quality Control Solutions Ltd.
Artis Biotech Co. Ltd.
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Guangzhou Juntang Technology Co., Ltd
TargetMol Chemicals Inc.
Shanghai YuZn Pharm. Technology Co.,Ltd.
LGC Science (Shanghai) Ltd.
CHINA ISOTOPE CO., LIMITED
