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ChemicalBook >> CAS DataBase List >> SGI 7079

SGI 7079

$36 - $2100
Product name: SGI 7079
CAS: 1239875-86-5
MF: C26H26FN7
MW: 455.53
EINECS:
MDL Number:MFCD28963942
Synonyms:3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile;SGI 7079;SGI-7079 /SGI7079;2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile;SGI-7079;SGI 7079;SGI7079;CS-2333;Benzeneacetonitrile, 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-;Tyro3,inhibit,SGI 7079,Inhibitor,Axl,SGI-7079,Mer,TAM Receptor,SGI7079

Price38 Properties Safety Information Description

38 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
American Custom Chemicals Corporation
Arctom
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
TRC

Package

1mg
2mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98%
Packaging1mg
Price$36
Updated2026-05-25
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Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98%
Packaging2mg
Price$43
Updated2026-05-25
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Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98%
Packaging5mg
Price$52
Updated2026-05-25
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Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98%
Packaging10mg
Price$64
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98%
Packaging25mg
Price$132
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98
Packaging50mg
Price$224
Updated2026-05-25
Buy

Manufactureraablocks
Product numberAA000L88
Product descriptionSGI-7079 98
Packaging100mg
Price$318
Updated2026-05-25
Buy

ManufacturerACHEMBLOCK
Product numberY229113
Product descriptionSGI-7079 97.00%
Packaging25MG
Price$235
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY229113
Product descriptionSGI-7079 97.00%
Packaging50MG
Price$305
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY229113
Product descriptionSGI-7079 97.00%
Packaging100MG
Price$445
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number8620DG
Product descriptionCID46870258
Packaging1mg
Price$133
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA771421
Product descriptionSGI-7079 98+%
Packaging5mg
Price$83
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA771421
Product descriptionSGI-7079 98+%
Packaging10mg
Price$130
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA771421
Product descriptionSGI-7079 98+%
Packaging2mg
Price$57
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA771421
Product descriptionSGI-7079 98+%
Packaging50mg
Price$425
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA771421
Product descriptionSGI-7079 98+%
Packaging100mg
Price$552
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA000L88	SGI-7079 98%	1mg	$36	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98%	2mg	$43	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98%	5mg	$52	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98%	10mg	$64	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98%	25mg	$132	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98	50mg	$224	2026-05-25	Buy
aablocks	AA000L88	SGI-7079 98	100mg	$318	2026-05-25	Buy
ACHEMBLOCK	Y229113	SGI-7079 97.00%	25MG	$235	2026-05-27	Buy
ACHEMBLOCK	Y229113	SGI-7079 97.00%	50MG	$305	2026-05-27	Buy
ACHEMBLOCK	Y229113	SGI-7079 97.00%	100MG	$445	2026-05-27	Buy
AK Scientific	8620DG	CID46870258	1mg	$133	2021-12-16	Buy
Ambeed	A771421	SGI-7079 98+%	5mg	$83	2021-12-16	Buy
Ambeed	A771421	SGI-7079 98+%	10mg	$130	2021-12-16	Buy
Ambeed	A771421	SGI-7079 98+%	2mg	$57	2021-12-16	Buy
Ambeed	A771421	SGI-7079 98+%	50mg	$425	2021-12-16	Buy
Ambeed	A771421	SGI-7079 98+%	100mg	$552	2021-12-16	Buy

Next Last

Properties

storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
color :Light yellow to yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321	Specific treatment (see … on this label).
P330	Rinse mouth.
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC₅₀s = 0.43 and 0.15 μM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G₁ phase. SGI-7079 synergistically increases the potency of erlotinib on EGFR inhibition. In a mouse xenograft model of non-small cell lung cancer, SGI-7079 dose-dependently inhibits tumor growth, an effect that is greater when used in combination with erlotinib.

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TargetMol Chemicals Inc.

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SGI 7079

Properties

Safety Information

Description

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