SIRAMESINE
|
- $75 - $3728.1
- Product name: SIRAMESINE
- CAS: 147817-50-3
- MF: C30H31FN2O
- MW: 454.58
- EINECS:
- MDL Number:MFCD00912182
- Synonyms:CS-1476;SIRAMESINE;1'-(4-(1-(4-fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine];1'-(4-(1-(4-FLUOROPHENYL)-1H-INDOL-3-YL)BUTYL)-3H-SPIRO[ISOBENZOFURAN-1,4'-PIPERIDINE].HCL;1'-[4-[1-(4-Fluorophenyl)-1H-indol-3-yl]-1-butyl]spiro[isobenzofuran-1(3H),4'-piperidine];1'-[4-[1-(4-fluorophenyl)indol-3-yl]butyl]spiro[1H-2-benzofuran-3,4'-piperidine];Spiro[isobenzofuran-1(3H),4'-piperidine], 1'-[4-[1-(4-fluorophenyl)-1H-indol-3-yl]butyl]-;1'-(4-(1-(4-fluorophenyl)-1H-indol-3-yl)butyl)-3H-spiro[isobenzofuran-1,4'-piperidine
45 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
Package
- 10mM*1mLinDMSO
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- Manufactureraablocks
- Product numberAA001F5X
- Product descriptionSiramesine >98%
- Packaging5mg
- Price$191
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001F5X
- Product descriptionSiramesine >98%
- Packaging10mg
- Price$285
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001F5X
- Product descriptionSiramesine >98%
- Packaging25mg
- Price$535
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001F5X
- Product descriptionSiramesine >98%
- Packaging50mg
- Price$858
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001F5X
- Product descriptionSiramesine >98%
- Packaging100mg
- Price$1347
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33748
- Product descriptionSiramesine 98%
- Packaging100MG
- Price$1710
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33748
- Product descriptionSiramesine 98%
- Packaging25MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33748
- Product descriptionSiramesine 98%
- Packaging5MG
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberB1297
- Product descriptionSiramesine
- Packaging5mg
- Price$310
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1297
- Product descriptionSiramesine
- Packaging25mg
- Price$680
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1297
- Product descriptionSiramesine
- Packaging10mg
- Price$469
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1297
- Product descriptionSiramesine
- Packaging50mg
- Price$1112
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1297
- Product descriptionSiramesine
- Packaging100mg
- Price$1729
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-14221
- Product descriptionSiramesine 98.98%
- Packaging100mg
- Price$1121
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14221
- Product descriptionSiramesine 98.98%
- Packaging50mg
- Price$703
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-14221
- Product descriptionSiramesine 98.98%
- Packaging25mg
- Price$428
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001F5X | Siramesine >98% | 5mg | $191 | 2026-05-28 | Buy |
| aablocks | AA001F5X | Siramesine >98% | 10mg | $285 | 2026-05-28 | Buy |
| aablocks | AA001F5X | Siramesine >98% | 25mg | $535 | 2026-05-28 | Buy |
| aablocks | AA001F5X | Siramesine >98% | 50mg | $858 | 2026-05-28 | Buy |
| aablocks | AA001F5X | Siramesine >98% | 100mg | $1347 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33748 | Siramesine 98% | 100MG | $1710 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33748 | Siramesine 98% | 25MG | $650 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33748 | Siramesine 98% | 5MG | $200 | 2026-05-27 | Buy |
| ApexBio Technology | B1297 | Siramesine | 5mg | $310 | 2026-05-06 | Buy |
| ApexBio Technology | B1297 | Siramesine | 25mg | $680 | 2026-05-06 | Buy |
| ApexBio Technology | B1297 | Siramesine | 10mg | $469 | 2026-05-06 | Buy |
| ApexBio Technology | B1297 | Siramesine | 50mg | $1112 | 2026-05-06 | Buy |
| ApexBio Technology | B1297 | Siramesine | 100mg | $1729 | 2026-05-06 | Buy |
| Arctom | HY-14221 | Siramesine 98.98% | 100mg | $1121 | 2026-05-26 | Buy |
| Arctom | HY-14221 | Siramesine 98.98% | 50mg | $703 | 2026-05-26 | Buy |
| Arctom | HY-14221 | Siramesine 98.98% | 25mg | $428 | 2026-05-26 | Buy |
Properties
Boiling point :611.4±55.0 °C(Predicted)
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :9.45±0.20(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4,8-15,21H,5-7,16-20,22H2
InChIKey :XWAONOGAGZNUSF-UHFFFAOYSA-N
SMILES :C12(CCN(CCCCC3C4=C(N(C5=CC=C(F)C=C5)C=3)C=CC=C4)CC1)C1=C(C=CC=C1)CO2
Density :1.19±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to at least 25 mg/ml)
pka :9.45±0.20(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChI :InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4,8-15,21H,5-7,16-20,22H2
InChIKey :XWAONOGAGZNUSF-UHFFFAOYSA-N
SMILES :C12(CCN(CCCCC3C4=C(N(C5=CC=C(F)C=C5)C=3)C=CC=C4)CC1)C1=C(C=CC=C1)CO2
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
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Description
Siramesine (Lu 28-179, 147817-50-3) is a σ2 selective agonist?(IC50’s: σ1 = 17nM, σ2 = 0.2nM).1?It produced non-sedating potent and long-last anxiolytic effects in rodents.2?Siramesine induced caspase-independent programmed cell death in various cancer cell lines?via?increased levels of ROS and lysosomal leakage.3,4,5?Mitochondrial destabilization via loss of membrane potential and increased ROS has also been offered as a mechanism of action for the triggering of cell death by Siramesine.6More related product prices
SiraMesine, Lu-28-179 ZM 336372 461054-93-3 TYRPHOSTIN AG 879 Cholesterol 115104-28-4 N-CARBOBENZOXY-DL-LEUCINE 1-(4-FLUOROPHENYL)PYRROLERelated product price
-
SiraMesine, Lu-28-179
$44-3728.1 -
ZM 336372
$12-1815 -
461054-93-3
$52-2500
Suppliers and manufacturers
Shanghai JiYi Biotechnology Co. Ltd.
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MedChemexpress LLC
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LETOPHARM LIMITED
Shanghai Lollane Biological Technology Co.,Ltd.