Sanggenon C
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- $117 - $2400
- Product name: Sanggenon C
- CAS: 80651-76-9
- MF: C40H36O12
- MW: 708.71
- EINECS:
- MDL Number:MFCD32004761
- Synonyms:sanggenone;Sanggenon C;(5aR,10aS)-2-[6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;2-[(1S)-6β-(2,4-Dihydroxybenzoyl)-5α-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexene-1β-yl]-5a,10a-dihydro-1,3,8,10aβ-tetrahydroxy-5aβ-(3-methyl-2-butenyl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;Sanggenone C;(5aR,10aS)-2-[(1S,5S,6R)-6-(2,4-Dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-11H-benzofuro[3,2-b][1]benzopyran-11-one;11H-Benzofuro[3,2-b][1]benzopyran-11-one, 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-5a,10a-dihydro-1,3,8,10a-tetrahydroxy-5a-(3-methyl-2-buten-1-yl)-, (5aR,10aS)-;(5aR,10aS)-2-((1S,2R,3S)-2-(2,4-Dihydroxybenzoyl)-2',4'-dihydroxy-5-methyl-1,2,3,6-tetrahydro-[1,1'-biphenyl]-3-yl)-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-en-1-yl)-5a,10a-dihydro-11H-benzofuro[3,2-b]chromen-11-one
18 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- 20mg
- 1000mg
- ManufacturerAK Scientific
- Product number8253AH
- Product descriptionSanggenoneC
- Packaging10mg
- Price$1126
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2564
- Product description2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN99593
- Product descriptionSanggenoneC
- Packaging20mg
- Price$383
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2421
- Product descriptionSanggenone C
- Packaging1mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2421
- Product descriptionSanggenone C
- Packaging20mg
- Price$790
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105480
- Product descriptionSanggenon C >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594266
- Product descriptionSanggenon C
- Packaging10mg
- Price$596.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594266
- Product descriptionSanggenon C
- Packaging20mg
- Price$841.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number30061
- Product descriptionSanggenone C
- Packaging1mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30061
- Product descriptionSanggenone C
- Packaging5mg
- Price$521
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number30061
- Product descriptionSanggenone C
- Packaging10mg
- Price$923
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0009613
- Product descriptionSanggenonC
- Packaging1mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0009613
- Product descriptionSanggenonC
- Packaging5mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDCS-069
- Product descriptionSanggenonC >98%,StandardReferencesGrade
- Packaging20mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberC74014
- Product descriptionSanggenonC 98%
- Packaging20mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product numberC74014
- Product descriptionSanggenonC 98%
- Packaging1000mg
- Price$2400
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8253AH | SanggenoneC | 10mg | $1126 | 2021-12-16 | Buy |
| ApexBio Technology | N2564 | 2-[(1S,5S,6R)-6-(2,4-dihydroxybenzoyl)-5-(2,4-dihydroxyphenyl)-3-methylcyclohex-2-en-1-yl]-1,3,8,10a-tetrahydroxy-5a-(3-methylbut-2-enyl)-[1]benzofuro[3,2-b]chromen-11-one | 20mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN99593 | SanggenoneC | 20mg | $383 | 2021-12-16 | Buy |
| AvaChem | 2421 | Sanggenone C | 1mg | $190 | 2021-12-16 | Buy |
| AvaChem | 2421 | Sanggenone C | 20mg | $790 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105480 | Sanggenon C >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594266 | Sanggenon C | 10mg | $596.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594266 | Sanggenon C | 20mg | $841.5 | 2021-12-16 | Buy |
| Cayman Chemical | 30061 | Sanggenone C | 1mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 30061 | Sanggenone C | 5mg | $521 | 2024-03-01 | Buy |
| Cayman Chemical | 30061 | Sanggenone C | 10mg | $923 | 2024-03-01 | Buy |
| ChemScene | CS-0009613 | SanggenonC | 1mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-0009613 | SanggenonC | 5mg | $300 | 2021-12-16 | Buy |
| DC Chemicals | DCS-069 | SanggenonC >98%,StandardReferencesGrade | 20mg | $280 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | C74014 | SanggenonC 98% | 20mg | $650 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | C74014 | SanggenonC 98% | 1000mg | $2400 | 2021-12-16 | Buy |
Properties
Melting point :> 240°C (dec.)
Boiling point :995.5±65.0 °C(Predicted)
Density :1.512
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Acetone (Slightly), Methanol (Slightly)
pka :6.61±0.60(Predicted)
form :Solid
color :Yellow
InChIKey :XETHJOZXBVWLLM-HUKCQOFTSA-N
SMILES :[C@@]12(C/C=C(/C)\C)C3=CC=C(O)C=C3O[C@]1(O)C(=O)C1=C(O)C([C@@H]3[C@H](C(=O)C4=CC=C(O)C=C4O)[C@@H](C4=CC=C(O)C=C4O)CC(C)=C3)=C(O)C=C1O2
Boiling point :995.5±65.0 °C(Predicted)
Density :1.512
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Acetone (Slightly), Methanol (Slightly)
pka :6.61±0.60(Predicted)
form :Solid
color :Yellow
InChIKey :XETHJOZXBVWLLM-HUKCQOFTSA-N
SMILES :[C@@]12(C/C=C(/C)\C)C3=CC=C(O)C=C3O[C@]1(O)C(=O)C1=C(O)C([C@@H]3[C@H](C(=O)C4=CC=C(O)C=C4O)[C@@H](C4=CC=C(O)C=C4O)CC(C)=C3)=C(O)C=C1O2
Safety Information
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Description
Sanggenone C is a flavonoid that has been found in mulberry bark and has diverse biological activities. It inhibits TNF-α- or IL-1β-induced polymorphonuclear leukocyte (PMN) adhesion to human synovial cells (HSCs; IC50s = 27.29 and 54.43 nM, respectively), as well as inhibits NF-κB activation in HSCs. Sanggenone C induces apoptosis and production of reactive oxygen species (ROS) in HT-29 cells when used at concentrations ranging from 10 to 40 μM. It decreases cell viability of HT-29 cells in vitro and reduces tumor growth in an HT-29 mouse xenograft model when administered at a dose of 10 mg/kg. Sanggenone C increases vertebrate column bone mineralization in a zebrafish model of prednisone-induced osteoporosis. It also attenuates cardiac hypertrophy and fibrosis and reduces activation of nuclear factor of activated T cells 2 (NFAT2) in a mouse model of pressure overload-induced cardiac hypertrophy.Related product price
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