Pipethanate

Pipethanate Struktur
4546-39-8
CAS-Nr.
4546-39-8
Englisch Name:
Pipethanate
Synonyma:
Pipethanate;Benzilic acid 2-piperidinoethyl ester;Hydroxydiphenylacetic acid 2-piperidinoethyl ester;α-Hydroxy-α,α-diphenylacetic acid 2-(1-piperidyl)ethyl ester;Benzeneacetic acid, α-hydroxy-α-phenyl-, 2-(1-piperidinyl)ethyl ester
CBNumber:
CB11179515
Summenformel:
C21H25NO3
Molgewicht:
339.43
MOL-Datei:
4546-39-8.mol

Pipethanate Eigenschaften

Schmelzpunkt:
168-169 °C
Siedepunkt:
444.1±24.0 °C(Predicted)
Dichte
1.155±0.06 g/cm3(Predicted)
pka
11.34±0.29(Predicted)

Sicherheit

Pipethanate Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Panpurol ,Nippon Shinyaku, Japan

Manufacturing Process

Pipethanate hydrochloride is dissolved in water and the solution is made alkaline by adding 10% sodium hydroxide solution. The crystals that are separated are filtered off and recrystallized from dilute ethanol. The monohydrate thereby obtained is dehydrated at 100°C under reduced pressure for 20 minutes. The products that are now in the form of a syrup due to loss of water of crystallization are further dehydrated for 2 days in a desiccator over phosphorus pentoxide whereupon the anhydrous pipethanate is obtained.
3.8 g of the anhydrous pipethanate prepared by the method described is dissolved in 15 cc of acetone, 18 g of purified ethyl bromide is added, and the mixture heated for 8 hours in a sealed tube at 100°C to 110°C. After cooling the crystals are separated and isolated by filtration. They are then washed with acetone to give 5.2 g (95.6%) of pipethanate ethylbromide with a decomposition point of 218°C to 220°C. The crystals are almost pure.

Therapeutic Function

Anticholinergic, Antiulcer

Pipethanate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Pipethanate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 3)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 9020 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24017 58

4546-39-8()Verwandte Suche:


  • Pipethanate
  • Benzilic acid 2-piperidinoethyl ester
  • Hydroxydiphenylacetic acid 2-piperidinoethyl ester
  • α-Hydroxy-α,α-diphenylacetic acid 2-(1-piperidyl)ethyl ester
  • Benzeneacetic acid, α-hydroxy-α-phenyl-, 2-(1-piperidinyl)ethyl ester
  • 4546-39-8
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