Pipethanate
- CAS No.
- 4546-39-8
- Chemical Name:
- Pipethanate
- Synonyms
- Pipethanate;Benzilic acid 2-piperidinoethyl ester;Hydroxydiphenylacetic acid 2-piperidinoethyl ester;α-Hydroxy-α,α-diphenylacetic acid 2-(1-piperidyl)ethyl ester;Benzeneacetic acid, α-hydroxy-α-phenyl-, 2-(1-piperidinyl)ethyl ester
- CBNumber:
- CB11179515
- Molecular Formula:
- C21H25NO3
- Molecular Weight:
- 339.43
- MDL Number:
- MOL File:
- 4546-39-8.mol
| Melting point | 168-169 °C |
|---|---|
| Boiling point | 444.1±24.0 °C(Predicted) |
| Density | 1.155±0.06 g/cm3(Predicted) |
| pka | 11.34±0.29(Predicted) |
| FDA UNII | P32MG14U83 |
Pipethanate Chemical Properties,Uses,Production
Originator
Panpurol ,Nippon Shinyaku, Japan
Definition
ChEBI: Pipethanate is a diarylmethane.
Manufacturing Process
Pipethanate hydrochloride is dissolved in water and the solution is made alkaline by adding 10% sodium hydroxide solution. The crystals that are separated are filtered off and recrystallized from dilute ethanol. The monohydrate thereby obtained is dehydrated at 100°C under reduced pressure for 20 minutes. The products that are now in the form of a syrup due to loss of water of crystallization are further dehydrated for 2 days in a desiccator over phosphorus pentoxide whereupon the anhydrous pipethanate is obtained.
3.8 g of the anhydrous pipethanate prepared by the method described is dissolved in 15 cc of acetone, 18 g of purified ethyl bromide is added, and the mixture heated for 8 hours in a sealed tube at 100°C to 110°C. After cooling the crystals are separated and isolated by filtration. They are then washed with acetone to give 5.2 g (95.6%) of pipethanate ethylbromide with a decomposition point of 218°C to 220°C. The crystals are almost pure.
Therapeutic Function
Anticholinergic, Antiulcer
Pipethanate Preparation Products And Raw materials
Pipethanate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 9020 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24023 | 58 |
| Supplier | Advantage |
|---|---|
| Shaanxi Didu New Materials Co. Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |