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OREXIN B (HUMAN)

OREXIN B (HUMAN) Struktur
205640-91-1
CAS-Nr.
205640-91-1
Englisch Name:
OREXIN B (HUMAN)
Synonyma:
HYPOCRETIN-2;Human orexin B;OREXIN B (HUMAN);HYPOCRETIN-2, HUMAN;OREXIN B HUMAN ≥98%;PubChem ID: 90479794;OREXINS OREXIN B HUMAN;OREXIN B (HUMAN) USP/EP/BP;Orexin B (human), ≥98% (HPLC);RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
CBNumber:
CB2384164
Summenformel:
C123H212N44O35S
Molgewicht:
2899.34
MOL-Datei:
205640-91-1.mol
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OREXIN B (HUMAN) Eigenschaften

Dichte
1.49±0.1 g/cm3(Predicted)
storage temp. 
-20°C
Wasserlöslichkeit
Soluble to 1 mg/ml in Water
Sequenz
H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Sicherheit

WGK Germany  3
HS Code  2937190000

OREXIN B (HUMAN) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Orexin B is a hypothalamic neuropeptide that regulates feeding behavior, wakefulness, and behavior under situations of high motivational relevance. It is an agonist of orexin (OX) receptors with IC50 values of 420 and 36 nM for human recombinant OX1 and OX2 receptors, respectively, expressed in CHO cells. It induces transient increases in intracellular calcium in CHO cells stably expressing OX1 and OX2 (EC50s = 2,500 and 60 nM, respectively) and in primary rat ventral tegmental area (VTA) dopaminergic neurons. Orexin B stimulates arachidonic acid release from CHO cells expressing human recombinant OX1 (EC50 = 4.17 nM). It also stimulates food intake in freely feeding mice and goldfish when administered at intracerebroventricular doses of 30 nmol and 10 ng/g, respectively.

Biochem/physiol Actions

Orexins/Hypocretins, Orexin A/ hypocretin-1 and Orexin B/ hypocretin-2, are excitatory neuropeptides that mediate there effects via two receptors, OX-1 and OX-2. Orexins are involved in food intake, obesity regulation, energy homeostasis and differentiation.

OREXIN B (HUMAN) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

OREXIN B (HUMAN) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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205640-91-1()Verwandte Suche:

(Pentan-2,4-dionato-O,O')silber Methylisocyanacetat Ethylisocyanacetat Aluminiumtris(2,4-pentandionato-O,O') 2-Methylpropylisocyanid Benzylisocyanid Tris(pentan-2,4-dionato)eisen(II) N-Butylisocyanid Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium 1,1,3,3-Tetramethylbutylisocyanat (Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II) Dichloro(ethylendiamin)platin (p-Toluolsulfonyl)methylisocyanid Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium Phenylselenol Kupfer(II)-4-oxopent-2-en-2-olat
  • REF DUPL: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
  • Orexin B (huMan) Hypocretin-2 (huMan)
  • OREXIN B HUMAN ≥98%
  • ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • HYPOCRETIN-2
  • HYPOCRETIN-2, HUMAN
  • H-ARG-SER-GLY-PRO-PRO-GLY-LEU-GLN-GLY-ARG-LEU-GLN-ARG-LEU-LEU-GLN-ALA-SER-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-MET-NH2
  • RSGPPGLQGRLQRLLQASGNHAAGILTM-NH2
  • OREXINS OREXIN B HUMAN
  • OREXIN B (HUMAN)
  • Orexin B (human), ≥98% (HPLC)
  • PubChem ID: 90479794
  • Orexin B (human) (trifluoroacetate salt)
  • Human orexin B
  • L-Methioninamide, L-arginyl-L-serylglycyl-L-prolyl-L-prolylglycyl-L-leucyl-L-glutaminylglycyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminyl-L-alanyl-L-serylglycyl-L-asparaginyl-L-histidyl-L-alanyl-L-alanylglycyl-L-isoleucyl-L-leucyl-L-threonyl-
  • OREXIN B (HUMAN) USP/EP/BP
  • 205640-91-1
  • C123H212N44O35S
  • C123H212N44O35S1
  • proteins
  • Peptide
  • Orexin receptor
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