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Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)

EC 1.1.1.42 Struktur
9028-48-2
CAS-Nr.
9028-48-2
Bezeichnung:
Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat)
Englisch Name:
EC 1.1.1.42
Synonyma:
IDH;ICDH;IDH1;MGC55806;MGC171441;MGC174090;EC 1.1.1.42;EC 1.1.1.42 TYPE I;EC 1.1.1.42 TYPE IV;:THREO-DS-ISOCITRATE
CBNumber:
CB8395171
Summenformel:
NULL
Molgewicht:
0
MOL-Datei:
Mol file
Request For Quotation

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Eigenschaften

storage temp. 
2-8°C
Aggregatzustand
solution (clear)
Farbe
yellow-brown
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
WGK Germany  3
F  10
HS Code  3507909090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .

Allgemeine Beschreibung

Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.

Biochem/physiol Actions

Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 55)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co 		+86-0371-86658258
sales@coreychem.com China 29914 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49391 58
Creative Enzymes 		1-516-855-7709
info@creative-enzymes.com United States 8748 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43348 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 16621234537
 zhangsn@titansci.com China 14113 59
Nanjing Sunlida Biological Technology Co., Ltd. 025-57798810
sales@sunlidabio.com China 3750 55
Shanghai BeiZhuo Biotech Co., Ltd. 021-61119791,13386096464
bzswkf@foxmail.com China 3924 50
Shanghai JONLN Reagent Co., Ltd. 400-0066400 13621662912
 422131432@qq.com China 9986 55

9028-48-2(Dehydrogenase, Isocitrat (Nicotinamidadenindinucleotidphosphat))Verwandte Suche:

Tris(pentan-2,4-dionato)eisen(II) Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium (Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II) Phenylselenol Dichloro(ethylendiamin)platin (p-Toluolsulfonyl)methylisocyanid (Pentan-2,4-dionato-O,O')silber 2-Methylpropylisocyanid Aluminiumtris(2,4-pentandionato-O,O') Benzylisocyanid Kupfer(II)-4-oxopent-2-en-2-olat Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium 1,1,3,3-Tetramethylbutylisocyanat N-Butylisocyanid Methylisocyanacetat Ethylisocyanacetat
  • THREO-DS-ISOCITRATE: NADP+ OXIDOREDUCTASE
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING]
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE I
  • THREO-DS-ISOCITRATE: NADP(+) OXIDOREDUCTASE[DECARBOXYLATING] TYPE IV
  • isocitrate dehydrogenase from porcine heart
  • ICDH
  • ISOCITRIC DEHYDROGENASE (NADP)
  • ISOCITRIC DEHYDROGENASE (NADP) TYPE I
  • ISOCITRIC DEHYDROGENASE (NADP) TYPE IV
  • ISOCITRATE DEHYDROGENASE
  • EC 1.1.1.42
  • EC 1.1.1.42 TYPE I
  • EC 1.1.1.42 TYPE IV
  • ISOCITRAT DEHYDROGENASE FROM PORCINE HEA RT, 3-8 U/MG
  • ISOCITRIC DEHYDROGENASE TYPE IV FROM*POR CINE HEART
  • ISOCITRATE DEHYDROGENASE FROM PORCINE HE ART, ~10 U/MG
  • ISOCITRIC DEHYDROGENASE TYPE I CRUDE*FRO M PORCINE H
  • isocitric dehydrogenase (nadp) from porcine heart
  • Recombinant Isocitrate Dehydrogenase
  • isocitric dehydrogenase
  • ICDH, threo-Ds-Isocitrate: NADP+ oxidoreductase
  • Isocitric Dehydrogenase (NADP) from porcine heart,threo-Ds-Isocitrate: NADP+ oxidoreductase, ICDH
  • Isocitrate dehydrogenase (NAD+) recombinant from Yeast, 50% glycerol solution
  • rICDH (NADP), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
  • rICDH (NAD), threo-Ds-Isocitrate: NAD oxidoreductase (decarboxylating)
  • IsoCltrate dehydrogenase
  • TPN-specific isocitrate dehydrogenase
  • TPN-linked isocitrate dehydrogenase
  • TPN-isocitrate dehydrogenase
  • TPN-dependent isocitrate dehydrogenase
  • Oxalosuccinic decarboxylase
  • Isocitrate Dehydrogenase preparation porcine heart
  • isocitric dehydrogenase type I crude*from porcine
  • Dehydrogenase, isocitrate (nicotinamide adenine dinucleotide phosphate)
  • ISOCITRIC DEHYDROGENASE HIGHLY PURIFIED FROM PORCIN
  • Isocitrate Dehydrogenase 1 (NADP+) huMan
  • IDH
  • IDH1
  • Isocitrate Dehydrogenase Cytoplasmic
  • MGC171441
  • MGC174090
  • MGC55806
  • Isocitric Dehydrogenase (NADP), Bacillus subtilis, recombinant from E. coli
  • Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
  • NADP-specific isocitric dehydyrogenase
  • NADPH-dependent isocitrate dehydrogenase
  • Isocitrate Dehydrogenase (NADP+) from Bacteria, Recombinant
  • Native Porcine Isocitric Dehydrogenase (NADP)
  • Isocitrate Dehydrogenase (NADP+) from Yeast, Recombinant
  • Recombinant Human IDH1 C-his8 Protein, His Tag
  • Recombinant Human IDH1 Protein, His Tag
  • Isocitrate dehydrogenase from Bacillus subtilis, Recombinant
  • :THREO-DS-ISOCITRATE
  • Isocitrate dehydrogenas
  • 9028-48-2
  • 1.1.x.x Acting on hydroxyl groups
  • Biochemicals and Reagents
  • BioChemical
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