Pyrazofurin
- CAS No.
- 30868-30-5
- Chemical Name:
- Pyrazofurin
- Synonyms
- PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
- CBNumber:
- CB5276253
- Molecular Formula:
- C9H13N3O6
- Molecular Weight:
- 259.22
- MDL Number:
- MFCD07995040
- MOL File:
- 30868-30-5.mol
- MSDS File:
- SDS
| Boiling point | 584.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.785±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO, Water (Slightly) |
| pka | 7.17±0.50(Predicted) |
| form | powder |
| color | white to light brown |
| optical activity | [α]/D -49 to -39°, c = 0.5 in H2O |
| Stability | Hygroscopic |
| EWG's Food Scores | 1 |
| FDA UNII | 4B15044GQZ |
| NCI Drug Dictionary | pyrazofurin |
Pyrazofurin price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1502 | Pyrazofurin ≥98% (HPLC) | 30868-30-5 | 5mg | $150 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1502 | Pyrazofurin ≥98% (HPLC) | 30868-30-5 | 25mg | $599 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | API0008977 | PYRAZOFURIN 95.00% | 30868-30-5 | 10MG | $666.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008977 | PYRAZOFURIN 95.00% | 30868-30-5 | 100MG | $3433.5 | 2021-12-16 | Buy |
| ChemScene | CS-0085864 | Pyrazofurin ≥98.0% | 30868-30-5 | 5mg | $400 | 2021-12-16 | Buy |
Pyrazofurin Chemical Properties,Uses,Production
Uses
Geldanamycin (G304500) derivative.
Definition
ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.
Biochem/physiol Actions
Pyrazofurin serves as an effective drug against HIV (human immuno virus), vaccinia virus, West Nile viral infection.
Enzyme inhibitor
This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.
Pyrazofurin Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrazofurin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9293 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55827 | 58 |
| BOC Sciences | 16314854226 | inquiry@bocsci.com | United States | 9713 | 58 |
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