| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:Arachidonoyl-2’-Fluoroethylamide
CAS:166100-37-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
BOC Sciences
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| Tel: |
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| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Arachidonoyl-2'-fluoroethylamide
CAS:166100-37-4
Purity:≥98% Remarks:Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. Arachidonoyl 2'-fluoroethy
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Arachidonoyl-2'-Fluoroethylamide
CAS:166100-37-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:Arachidonyl-2’-fluoroethylamide
CAS:166100-37-4
Purity:NULL Package:10mg;1mg;2.5mg;25mg;5mg Remarks:NULL
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:2-FLUORO AEA
CAS:166100-37-4
Purity:98% Package:100mg (solution); 10mg (solution); 5mg (solution); 50mg (solution) Remarks:Medbio
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| | 2'-FLUORO AEA Basic information |
| Product Name: | 2'-FLUORO AEA | | Synonyms: | FLUOROETHYLEICOSATETRAENAMIDE;ARACHIDONOYL 2'-FLUOROETHYLAMIDE;AFEA;AEA, 2'-FLUORO;ANANDAMIDE, 2'-FLUORO;2'-FLUORO AEA;2'-FLUORO ANANDAMIDE;N-(2-FLUOROETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE | | CAS: | 166100-37-4 | | MF: | C22H36FNO | | MW: | 349.53 | | EINECS: | | | Product Categories: | | | Mol File: | 166100-37-4.mol |  |
| | 2'-FLUORO AEA Chemical Properties |
| Boiling point | 496.0±45.0 °C(Predicted) | | density | 0.925±0.06 g/cm3(Predicted) | | solubility | DMF: 10 mg/ml; DMSO: 7 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (1:1): 8 mg/ml | | pka | 15.24±0.46(Predicted) |
| | 2'-FLUORO AEA Usage And Synthesis |
| Description | Arachidonoyl-2'-fluoroethylamide (2-fluoro AEA) is an analog of anandamide in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution adds considerably increased binding affinity for the CB1 receptor (Kis = 26.7 and 908 nM for CB1 and CB2, respectively). It also contributes additional selectivity, in that binding to CB2 is decreased relative to AEA.1 However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme. | | Uses | Arachidonoyl-2'-fluoroethylamide is a CB1 receptor agonist and an analog of Anandamide (A637220), which is an endogenous cannabinoid and TRPV1 receptor agonist. | | References | 1. Lin, S., Khanolkar, A.D., Fan, P., et al. Novel analogues of arachidonylethanolamide (anandamide): Affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability J. Med. Chem. 41(27),5353-5361(1998). |
| | 2'-FLUORO AEA Preparation Products And Raw materials |
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