| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:(±)-2-Methyl Arachidonoyl-2’-Fluoroethylamide
CAS:166100-39-6
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:(±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide
CAS:166100-39-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:(+/-)-2-Methylarachidonoyl-2'-fluoroethylamide >=95%, ethanol solution
CAS:166100-39-6
Purity:95%, ethanol solution Package:5mg Remarks:NULL
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| Company Name: |
MedBioPharmaceutical Technology Inc
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| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:O-689
CAS:166100-39-6
Purity:98% Package:10mg (solution); 50mg (solution); 1mg (solution); 5mg (solution) Remarks:Medbio
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| Company Name: |
Suzhou Zhixin Biotechnology Co., Ltd.
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| Tel: |
0512-65118909 15162312715 |
| Email: |
sales@szzxbio.com |
| Products Intro: |
Product Name:Met-F-AEA
CAS:166100-39-6
Purity:98%+ Package:1g;10g;100g
|
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| Product Name: | O-689 | | Synonyms: | (+/-)-N-(2-FLUOROETHYL)-2-METHYL-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE;O-689;(+/-)-2-METHYLARACHIDONOYL-2'-FLUOROETHYLAMIDE;(+/-)-2-METHYLARACHIDONYL-2'-FLUOROETHYLAMIDE;2-METHYL-2'-FLUORO AEA;F-2-ME-AN;FLUOROMETHANANDAMIDE;(+/-)-2-METHYLARACHIDONOLY-2'*-FLUOROETHYLAMIDE | | CAS: | 166100-39-6 | | MF: | C23H38FNO | | MW: | 363.55 | | EINECS: | 200-578-6 | | Product Categories: | | | Mol File: | 166100-39-6.mol |  |
| | O-689 Chemical Properties |
| Boiling point | 503.6±50.0 °C(Predicted) | | density | 0.921±0.06 g/cm3(Predicted) | | Fp | 14 °C | | storage temp. | −20°C | | solubility | DMF: >10 mg/ml; DMSO: >30 mg/ml; Ethanol: >100 mg/ml; Ethanol:PBS (1:2): 8.5 mg/ml; PBS (pH 7.2): <100 μg/ml | | pka | 14.98±0.46(Predicted) | | form | ethanol solution |
| | O-689 Usage And Synthesis |
| Description | (±)-2-Methyl arachidonoyl-2''-fluoroethylamide (2-Methyl-2''-fluoro AEA) is an analog of anandamide (AEA) in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. This substitution confers considerably increased binding affinity for the CB1 receptor (Ki = 5.7 nM in rat brain). It also confers additional selectivity, in that binding to CB2 is decreased relative to AEA. However, the in vivo activity of 2-fluoro AEA is enhanced much less than the binding affinity, because the analog remains a good substrate for FAAH and is rapidly hydrolyzed by this enzyme. 2-Methyl-2''-fluoro AEA is further modified by the addition of an α-methyl group at the C-2 position of arachidonic acid. This substitution confers enhanced metabolic stability. 2-Methyl-2''-fluoro AEA can fully substitute for Δ9-THC in animal self-administration tests, whereas AEA and 2-fluoro AEA cannot. |
| | O-689 Preparation Products And Raw materials |
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