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1006388-38-0

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1006388-38-0 Structure

1006388-38-0 Structure
IdentificationBack Directory
[Name]

Cenupatide
[CAS]

1006388-38-0
[Synonyms]

Cenupatide
Cenupatide TFA
AC-ARG-AIB-ARG-Α(ME)PHE-NH2
[Molecular Formula]

C28H47N11O5
[MOL File]

1006388-38-0.mol
[Molecular Weight]

617.76
Chemical PropertiesBack Directory
[density ]

1.34±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

12.99±0.46(Predicted)
[color ]

White to off-white
[Sequence]

Ac-Arg-{Aib}-Arg-{aMePhe}-NH2
Hazard InformationBack Directory
[Uses]

Cenupatide (UPARANT) is a Urokinase-type plasminogen activator receptor (uPAR) inhibitor. Cenupatide has anti-angiogenic and anti-inflammatory efficacy[1].
[References]

[1] Filippo Locri, et al. UPARANT is an effective antiangiogenic agent in a mouse model of rubeosis iridis. J Mol Med (Berl). 2019, 97, 9.
[2] Cai Yuan, et al. Development of inhibitors for uPAR: blocking the interaction of uPAR with its partners. Drug Discov Today. 2021, 26, 4. DOI:10.1016/j.drudis.2021.01.016
Spectrum DetailBack Directory
[Spectrum Detail]

Cenupatide(1006388-38-0)1HNMR
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