| Identification | More | [Name]
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE | [CAS]
10068-07-2 | [Synonyms]
METHYL 3-HYDROXY-5-ISOXAZOLECARBOXYLATE
METHYL 3-HYDROXYISOXAZOLE-5-CARBOXYLATE
METHYL 3-HYDROXYL-5-ISOXAZOLECARBOXYLATE
3-HYDROXYISOXAZOLE-5-CARBOXYLIC ACID*MET HYL ESTER
METHYL 3-OXOOXAZOLE-5-CARBOXYLATE | [Molecular Formula]
C5H5NO4 | [MDL Number]
MFCD00062870 | [Molecular Weight]
143.1 | [MOL File]
10068-07-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Yellow Powder | [Melting point ]
160-163 °C(lit.)
| [Boiling point ]
261.15°C (rough estimate) | [density ]
1.5918 (rough estimate) | [refractive index ]
1.5820 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform, Ethanol, Ether, Ethyl Acetate, Methanol | [form ]
Powder | [pka]
11.25±0.40(Predicted) | [color ]
Light Yellow | [Usage]
An interesting intermediate | [InChI]
InChI=1S/C5H5NO4/c1-9-5(8)3-2-4(7)6-10-3/h2H,1H3,(H,6,7) | [InChIKey]
BBFWUUBQSXVHHZ-UHFFFAOYSA-N | [SMILES]
O1C(C(OC)=O)=CC(=O)N1 | [CAS DataBase Reference]
10068-07-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29349990 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Light Yellow Powder | [Uses]
Methyl 3-hydroxy-5-isoxazolecarboxylate was used in the enantioselective synthesis of a key precursor to the tetracycline antibiotics. It was also used in the preparation of formamidinopiperidine analog, an N-amidinopiperidine compound. | [Uses]
An interesting intermediate | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 20, p. 965, 1977 DOI: 10.1021/jm00217a023 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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