| Identification | Back Directory | [Name]
2-(3,4-dimethoxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide | [CAS]
1013213-84-7 | [Synonyms]
Carbonic anhydrase inhibitor 6
2-(3,4-dimethoxyphenyl)-N-(4-sulfamoylphenethyl)quinoline-4-carboxamide
2-(3,4-dimethoxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]quinoline-4-carboxamide
4-Quinolinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-2-(3,4-dimethoxyphenyl)- | [Molecular Formula]
C26H25N3O5S | [MOL File]
1013213-84-7.mol | [Molecular Weight]
491.56 |
| Hazard Information | Back Directory | [Uses]
Carbonic anhydrase inhibitor 6 (compound 9b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 9.7 nM, 35.2 nM, 88.5 nM, and 91.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1]. | [References]
[1] Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247. DOI:10.1016/j.ejmech.2022.114247 |
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OTAVA chemicals
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PHARMEKS Ltd.
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