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Monoacetylcadaverine hydrochloride is a metabolite of the endogenous polyamine cadaverine[1]. | [Biological Activity]
Monoacetylcadaverine is a metabolite of the endogenous polyamine cadaverine.1 It is formed from cadaverine via acetylation in the nuclear and microsomal fractions of isolated mouse brain.2 Plasma levels of monoacetylcadaverine are increased in patients with schizophrenia.3 | [References]
1.van den Berg, G.A., Muskiet, F.A., Kingma, A.W., et al.Simultaneous gas-chromatographic determination of free and acetyl-conjugated polyamines in urineClin. Chem.32(10)1930-1937(1986)
2.Ortiz, J.G., Giacobini, E., and Schmidt-Glenewinkel, T.Acetylation of polyamines in mouse brain: Subcellular and regional distributionJ. Neurosci. Res.9(2)193-201(1983)
3.Dolezalova, H., and Kauco, M.S.Monoacylcadaverines in the blood of schizophrenic patientsJ. Chromatogr.146(1)67-76(1978)
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