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1030097-65-4

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1030097-65-4 Structure

1030097-65-4 Structure

Identification	Back Directory
[Name] PAT1inh-A0030
[CAS] 1030097-65-4
[Synonyms] PAT1inh-A0030
[Molecular Formula] C17H18N4O3
[MOL File] 1030097-65-4.mol
[Molecular Weight] 326.35

Chemical Properties	Back Directory
[Boiling point ] 522.0±60.0 °C(predicted)
[density ] 1.277±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 2.16±0.50(predicted)

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[Uses] PAT1inh-A0030 is a selective PAT1 (SLC26A6) inhibitor (IC50= 1.0 μM). PAT1inh-A0030 inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption. PAT1inh-A0030 can be used in the study of intestinal diseases related to CF[1].
[References] [1] Chu T, et al. Selective isoxazolopyrimidine PAT1 (SLC26A6) inhibitors for therapy of intestinal disorders. RSC Med Chem. 2023 Sep 14;14(11):2342-2347. DOI:10.1039/d3md00302g

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Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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