ChemicalBook--->CAS DataBase List--->103404-75-7

103404-75-7

103404-75-7 Structure

103404-75-7 Structure
IdentificationMore
[Name]

D-LUCIFERIN SODIUM SALT
[CAS]

103404-75-7
[Synonyms]

D-Luciferin Sodium
D-LUCIFERIN SODIUM SALT
D-LUCIFERINSODIUMSALT,99%
D-Leciferin Sodium Salt
D-LUCIFERIN, MONOSODIUM SALT
FIREFLY LUCIFERIN SODIUM SALT
KIT HP TOTAL RNA EZNA 5 TESTS
LUCIFERIN, SODIUM SALT MONOHYDRATE
D-LUCIFERIN SODIUM SALT MONOHYDRATE
D(-)-LUCIFERIN SODIUM SALT MONOHYDRATE
D-LUCIFERIN SODIUM LYOPHILIZED FIREFLY
D-LUCIFERIN SODIUM SALT MONOHYDRATE, 98+%
D-LUCIFERIN,SODIUM SALT MONOHYDRATE (SYNTH)
D-Luciferin, sodium salt *CAS#: 103404-75-7*
D-Luciferin Firefly, sodiuM salt Monohydrate
D-LUCIFERIN SODIUM SALT MONOHYDRATE SYNTHETIC
FIREFLY LUCIFERIN MONOSODIUM SALT MONOHYDRATE
(S)-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-2-THIAZOLINE-4-CARBOXYLIC ACID SODIUM SALT
4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLECAEBOXYLIC ACID SODIUM SALT
4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLE-CARBOXYLIC ACID SODIUM SALT
(S)-4,5-Dihydro-2-(6-hydroxybenzothiazol-2-yl)thiazole-4-carboxylic acid sodium salt
D-(-)-2-[6'-HYDROXY-2'-BENZOTHIAZOLYL]DELTA-THIAZOLINE-4-CARBOXYLIC ACID SODIUM SALT
(4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt
(S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4 thiazolecarboxylic acid Sodium salt salt
4-Thiazolecarboxylicacid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, sodium salt (1:1), (4S)-
Firefly luciferin sodium salt, (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid sodium salt, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid sodium salt
[EINECS(EC#)]

600-430-4
[Molecular Formula]

C11H7N2NaO3S2
[MDL Number]

MFCD00044938
[Molecular Weight]

302.3
[MOL File]

103404-75-7.mol
Chemical PropertiesBack Directory
[Appearance]

Yellow powder
[storage temp. ]

−20°C
[solubility ]

H2O: soluble
[form ]

lyophilized powder
[color ]

Yellow
[biological source]

synthetic
[Water Solubility ]

H2O: soluble
[InChI]

InChI=1/C11H8N2O3S2.Na.H/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;;/h1-3,7,14H,4H2,(H,15,16);;/t7-;;/s3
[InChIKey]

ZONJDNKUJJUQCK-DCFBZVEJNA-N
[SMILES]

C([C@H]1CSC(C2=NC3C=CC(O)=CC=3S2)=N1)(=O)O.[NaH] |&1:1,r|
[CAS DataBase Reference]

103404-75-7(CAS DataBase Reference)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

R36/37/38:Irritating to eyes, respiratory system and skin .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
[WGK Germany ]

3
[F ]

10-21-23
[HS Code ]

29349990
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

D-Luciferin is a chemiluminescent substrate of firefly luciferase. It produces light upon oxidative decarboxylation by luciferase in the presence of ATP. D-luciferin can be employed to assay the expression of the luciferase gene linked to a promoter of interest. Alternatively, D-luciferin and luciferase can be used to assess ATP availability in cellular or biochemical assays.
[Chemical Properties]

Yellow powder
[Uses]

D-Luciferin sodium salt is substrate for firefly luciferase, properties and use in assays of ATP and luciferase.
[Uses]

Luciferin is used for luciferase assays and determination of ATP.
[General Description]

D-Luciferin is mainly produced in bioluminescent organisms. It can simply circulate across the blood testis barrier, blood brain barrier and the blood placenta barrier. This small molecule is sensitive to light and oxygen. D-Luciferin is also sensitive to moisture in its powder form.
[Biological Activity]

D-Luciferin sodium salt is a firefly luciferase substrate (Km = ~2 μM). Used in much standard bioluminescence imaging (BLI) techniques, including monitoring tumor growth and investigating intracellular signaling activity in vitro and in vivo. Cell permeable. Emission maximum = 562 nm.
[Synthesis]

Produced by the condensation of resorcinol with phthalic anhydride in the presence of zinc chloride or sulfuric acid, which is then converted to the sodium salt.

[storage]

-20°C
[References]

[1] LEMBERT N. Firefly luciferase can use L-luciferin to produce light.[J]. Biochemical Journal, 1996, 317 ( Pt 1): 273-277. DOI: 10.1042/bj3170273
Spectrum DetailBack Directory
[Spectrum Detail]

D-LUCIFERIN SODIUM SALT(103404-75-7)1HNMR
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

D-Luciferin sodium salt monohydrate, 98+%(103404-75-7)
[Sigma Aldrich]

103404-75-7(sigmaaldrich)
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