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1042433-41-9

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1042433-41-9 Structure

1042433-41-9 Structure
IdentificationBack Directory
[Name]

GSK-1520489A
[CAS]

1042433-41-9
[Synonyms]

GSK-1520489A
[Molecular Formula]

C21H23N5O3S
[MOL File]

1042433-41-9.mol
[Molecular Weight]

425.5
Chemical PropertiesBack Directory
[density ]

1.336±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 11 mg/mL (25.85 mM);Ethanol: Insoluble
[form ]

Solid
[pka]

14.63±0.46(Predicted)
[color ]

White to off-white
[Water Solubility ]

Water: Insoluble
Hazard InformationBack Directory
[Uses]

GSK-1520489A is a PKMYT1 (active protein kinase) inhibitor (IC50=115 nM, Ki=10.94 nM)[1].
[Biological Activity]

GSK-1520489A(EX-A5430) is an active Protein Kinase, Membrane Associated Tyrosine/Threonine 1 (PKMYT1) inhibitor.
[References]

[1] Platzer C, et al. Bioorg Med Chem. 2018 Aug 7;26(14):4014-4024.
Spectrum DetailBack Directory
[Spectrum Detail]

GSK-1520489A(1042433-41-9)1HNMR
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