ChemicalBook--->CAS DataBase List--->1068-57-1

1068-57-1

1068-57-1 Structure

1068-57-1 Structure
IdentificationMore
[Name]

Acethydrazide
[CAS]

1068-57-1
[Synonyms]

ACETHYDRAZIDE
ACETIC ACID HYDRAZIDE
ACETIC HYDRAZIDE
ACETOHYDRAZIDE
ACETYLHYDRAZINE
AKOS 90782
MONOACETYLHYDRAZINE
N-ACETYL HYDRAZINE
374
Acetyl hydrazide
acetylhydrazide
acetyl-hydrazin
ENT-61241
Ethanehydrazonic acid
ethanehydrazonicacid
Hydrazid kyseliny octove
hydrazidkyselinyoctove
Hydrazine, Acetyl-
N-Acetyldiamine
NSC 53155
[EINECS(EC#)]

213-948-7
[Molecular Formula]

C2H6N2O
[MDL Number]

MFCD00007610
[Molecular Weight]

74.08
[MOL File]

1068-57-1.mol
Chemical PropertiesBack Directory
[Appearance]

White moist crystals and chunks
[Melting point ]

58-68 °C (lit.)
[Boiling point ]

129 °C/18 mmHg (lit.)
[density ]

1.0968 (rough estimate)
[refractive index ]

1.4264 (estimate)
[Fp ]

>230 °F
[storage temp. ]

Flammables area
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Moist Crystals and Chunks
[pka]

13.46±0.18(Predicted)
[color ]

White
[Water Solubility ]

soluble
[Sensitive ]

Hygroscopic
[BRN ]

506165
[InChIKey]

OFLXLNCGODUUOT-UHFFFAOYSA-N
[CAS DataBase Reference]

1068-57-1(CAS DataBase Reference)
[NIST Chemistry Reference]

Acetic acid, hydrazide(1068-57-1)
[EPA Substance Registry System]

1068-57-1(EPA Substance)
Questions And AnswerBack Directory
[Description]

Acethydrazide is an essential organic intermediate mainly used to synthesize nifuratrone in the pharmaceutical industry. It belongs to the hydrazine/hydrazone group, which plays an important role in the anti-microbial activity. Recently, Acethydrazide has gained significant importance due to its anti-tuberculosis activity. A disease caused by parasites represents a major world health problem with limited therapeutic options. Acethydrazide was synthesized from the reaction between ethyl acetate and hydrazine hydrate in methanol solvent and purified[1-2].
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

R22:Harmful if swallowed.
R36/38:Irritating to eyes and skin .
[Safety Statements ]

S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
[RIDADR ]

1759
[WGK Germany ]

1
[RTECS ]

AI1225000
[F ]

3-8-10
[TSCA ]

Y
[HazardClass ]

6.1
[PackingGroup ]

II
[HS Code ]

29280090
[Safety Profile]

Poison by ingestion, subcutaneous, and intraperitoneal routes. Mutation data reported. Exposure can cause hemolysis and liver damage. See also PHENYLHYDRAZINE. When heated to decomposition it emits toxic fumes of NOX,.
[Toxicity]

LD50 oral in bird - wild: 42200ug/kg
Raw materials And Preparation ProductsBack Directory
[Raw materials]

2-N-BUTOXYETHYL METHACRYLATE-->Acetamide,N-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)--->NSC45006-->2-butanone (1-methylpropylidene)hydrazone-->Hydrazinecarboxylic acid, 2-acetyl-, 1,1-dimethylethyl ester (9CI)-->3,6-Dithia-1,8-octanediol-->Ethyl acetimidate hydrochloride-->Dibenzoylmethane-->Benzoylacetone-->Acetamide
[Preparation Products]

2-Mercapto-5-methyl-1,3,4-thiadiazole-->5-Methyl-1,3,4-oxadiazol-2(3H)-one-->FlubroMazolaM-->2-Amino-5-methyl-1,3,4-thiadiazole-->Ethyl 5-Methyl-1,3,4-thiadiazole-2-carboxylate-->Methylamine nitrate-->5-METHYL-1,3,4-OXADIAZOL-2-YLAMINE-->(R)-(-)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Acethydrazide(1068-57-1).msds
Hazard InformationBack Directory
[Chemical Properties]

White moist crystals and chunks
[Uses]

Acetohydrazide is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis.
[Definition]

ChEBI: A carbohydrazide that is hydrazine in which one of the hydrogens is replaced by an acetyl group.
[Purification Methods]

Acetic hydrazide crystallises as needles from EtOH. It reduces NH3/AgNO3. [Beilstein 2 H 191, 2 IV 435.]
[References]

[1] S. Nzikayel, A. Ec, Akpan Ij. “Synthesis, FTIR and Electronic Spectra Studies of Metal (II) Complexes of Acethydrazide Derivative.” Medicinal Chemistry 8 1 (2018): 26–28.
[2] S. Pakdehi, A. S. Moghaddam, M. Sohrabi. “Liquid phase hydrogenation of acethydrazone to N’-methyl acethydrazide over Pd/γ-Al2O3 catalyst.” Brazilian Journal of Chemical Engineering 27 1 (2010): 145–152.
Spectrum DetailBack Directory
[Spectrum Detail]

Acethydrazide(1068-57-1)MS
Acethydrazide(1068-57-1)1HNMR
Acethydrazide(1068-57-1)13CNMR
Acethydrazide(1068-57-1)IR1
Acethydrazide(1068-57-1)IR2
Acethydrazide(1068-57-1)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

Acethydrazide, 95%(1068-57-1)
[Alfa Aesar]

Acetic hydrazide, 96%(1068-57-1)
[Sigma Aldrich]

1068-57-1(sigmaaldrich)
[TCI AMERICA]

Acetohydrazide,>98.0%(T)(1068-57-1)
1068-57-1 suppliers list
Company Name: Jiangsu Suoteng New Material Technology Co, Ltd.
Tel: +8618114870532 , +8618114870532
Website: www.jssunton.com/
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-81148696 +86-15536356810 , +86-15536356810
Website: https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-221/
Company Name: Henan Bao Enluo International TradeCo.,LTD
Tel: +86-17331933971 +86-17331933971 , +86-17331933971
Website: baoenluo.guidechem.com/
Company Name: Henan Fengda Chemical Co., Ltd
Tel: +86-371-86557731 +86-13613820652 , +86-13613820652
Website: http://www.fdachem.com
Company Name: hebei hongtan Biotechnology Co., Ltd
Tel: +852-6619 3215 +86-17731935328 , +86-17731935328
Website: hbht123.com
Company Name: HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Tel: +8615350851019 , +8615350851019
Website: www.86-ss.com/
Company Name: Hi-Tech Chemistry Corp
Tel: 0519-86626038
Website: www.eastfine.net
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: +86-0551-65418679 +8618949832763 , +8618949832763
Website: http://www.tnjchem.com
Company Name: Tianjin Zhongxin Chemtech Co., Ltd.
Tel: 86-22-66880623 +8618622897568 , +8618622897568
Website: http://www.tjzxchem.com
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: Jinan Jianfeng Chemical Co., Ltd
Tel: +86-0531-88110457 +86-15562555968 , +86-15562555968
Website: www.jianfengchemical.com/
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Website: www.hubeijusheng.com
Company Name: Jinan Finer Chemical Co., Ltd
Tel: +86-531-88989536 +86-15508631887 , +86-15508631887
Website: www.finerchem.com
Company Name: Jinan Gongchuang Pharmaceutical Technology Co., Ltd.
Tel: 13287783460
Website: www.chemicalbook.com/ShowSupplierProductsList939347/0_EN.htm
Company Name: Hubei xin bonus chemical co. LTD
Tel: 86-13657291602
Website: www.chemicalbook.com/ShowSupplierProductsList1549548/0_EN.htm
Company Name: Changzhou Carman Chemical Co., Ltd.
Tel: 15061933924
Website: www.chemicalbook.com/ShowSupplierProductsList1090088/0_EN.htm
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.chemicalbook.com/ShowSupplierProductsList454175/0_EN.htm
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Tags:1068-57-1 Related Product Information
55896-93-0 123-54-6 103-90-2 75-36-5 123-33-1 50-78-2 77-90-7 539-88-8 32687-78-8 114-83-0 108-24-7 787-84-8 4551-69-3 1596-84-5 92-43-3 103-82-2 4149-06-8 550-74-3

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.