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1071676-04-4

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1071676-04-4 Structure

1071676-04-4 Structure
IdentificationBack Directory
[Name]

6-Methoxyldihydrochelerythrine chloride
[CAS]

1071676-04-4
[Synonyms]

Angoline hydrochloride
6-Methoxyldihydrochelerythrine chloride
[Molecular Formula]

C22H22ClNO5
[MOL File]

1071676-04-4.mol
[Molecular Weight]

415.87
Chemical PropertiesBack Directory
[Melting point ]

267-268 °C
[storage temp. ]

Store at -20°C
Hazard InformationBack Directory
[Uses]

Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
[References]

[1] Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91. DOI:10.1016/j.phymed.2014.04.001
Spectrum DetailBack Directory
[Spectrum Detail]

6-Methoxyldihydrochelerythrine chloride(1071676-04-4)1HNMR
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