| Identification | Back Directory | [Name]
9H-Purine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy- | [CAS]
109304-06-5 | [Synonyms]
9H-Purine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy- | [Molecular Formula]
C11H13FN4O4 | [MOL File]
109304-06-5.mol | [Molecular Weight]
284.25 |
| Chemical Properties | Back Directory | [Melting point ]
146 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
567.6±60.0 °C(Predicted) | [density ]
1.79±0.1 g/cm3(Predicted) | [pka]
12.58±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
2’-Deoxy-2’-fluoroarabino-O6-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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