ChemicalBook--->CAS DataBase List--->1124381-69-6

1124381-69-6

1124381-69-6 Structure

1124381-69-6 Structure
IdentificationBack Directory
[Name]

S-99
[CAS]

1124381-69-6
[Synonyms]

S-99
S99;S 99
S-99 ≥95%
S-99 (Neuprotect)
N-(5-(isopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide
3-Pyridinecarboxamide, N-[5-[(1-methylethyl)amino]-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-
[Molecular Formula]

C16H15F3N6O
[MOL File]

1124381-69-6.mol
[Molecular Weight]

364.33
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: soluble,Ethanol: 4mg/mL
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H317
[Precautionary statements ]

P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard InformationBack Directory
[Uses]

ASK1-IN-5 (S-99) is an inhibitor of apoptosis signal-regulated kinase 1 (ASK1) and is useful in the study of autoimmune and neurodegenerative diseases[1].
[Biological Activity]

S-99 is an inhibitor of apoptosis signal-regulating kinase 1 (ASK1; IC50 = 42 nM).1
[IC 50]

ASK1
[storage]

-20°C
[References]

1.Swinnen, D., Jorand-Lebrun, C., Grippi-Vallotton, T., et al.Triazolopyridine compounds and their use as ask inhibitors(2009)
Spectrum DetailBack Directory
[Spectrum Detail]

S-99(1124381-69-6)1HNMR
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