| Identification | More | [Name]
4',7-Dimethoxyisoflavone | [CAS]
1157-39-7 | [Synonyms]
4',7-DIMETHOXYISOFLAVONE
4',7-DIMETHOXYISOFLAVONE DIMETHYL ETHER
7,4'-DIMETHOXYISOFLAVONE
DAIDZEIN DIMETHYL ETHER
DIMETHOXYISOFLAVONE,4',7- | [Molecular Formula]
C17H14O4 | [MDL Number]
MFCD00075889 | [Molecular Weight]
282.29 | [MOL File]
1157-39-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
161-163°C | [Boiling point ]
452.8±45.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [λmax]
260nm(MeOH)(lit.) | [BRN ]
265550 | [LogP]
3.430 (est) | [CAS DataBase Reference]
1157-39-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
10 | [HS Code ]
2932.99.7000 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents. | [Uses]
4',7-Dimethoxyisoflavone is a flavonoid compound. It is isolated from the leaves of Albizzia lebbeck, which shows antifungal activity. It has been shown to inhibit the proliferation of cancer cells in vitro. It also inhibits the activity of a-ring hydroxylase and epoxide hydrolase. The optimum concentration for 4',7-dimethoxyisoflavone is 10 μM. This chemical is metabolized by cytochrome P450 enzymes, with bosentan as an inhibitor. Bosentan also inhibits the formation rate of 4',7-dimethoxyisoflavone by hydrogen bonding with this chemical in vitro. | [Biological Activity]
4', 7-Dimethoxyisoflavone is a flavonoid isolated from Albizia laparvais with antifungal effect. | [in vitro]
4',7-Dimethoxyisoflavone shows antifungal activity against some plant pathogenic fungi tested in vitro, and the sensitivity of different fungi to this chemical varied considerably. | [target]
| Human Endogenous Metabolite < span> | |
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