| Identification | More | [Name]
Tetradifon | [CAS]
116-29-0 | [Synonyms]
2,4,4',5-TETRACHLORODIPHENYL SULFONE
DUPHAR(R)
DURACIDE
P-CHLOROPHENYL-2,4,5-TRICHLOROPHENYL SULFONE
TEDION
TEDION V-18
TEDION V-18(R)
TEDONE
TETRADIFON
1,2,4-trichloro-5-((4-chlorophenyl)sulfonyl)-benzen
1,2,4-trichloro-5-((4-chlorophenyl)-sulfonyl)benzene
1,2,4-Trichloro-5-[(4-chlorophenyl)sulfonyl]benzene
1,2,4-trichloro-5-[(4-chlorophenyl)sulfonyl]-Benzene
2,4,4',5-Tetrachloor-difenyl-sulfon
2,4,4',5-Tetrachlor-diphenyl-sulfon
2,4,4',5-Tetracloro-difenil-solfone
2,4,4’,5-tetrachloor-difenyl-sulfon
2,4,4’,5-tetrachlor-diphenyl-sulfon
2,4,4’,5-tetrachlorodiphenylsulphone(british)
2,4,4’,5-tetracloro-difenil-solfone | [EINECS(EC#)]
204-134-2 | [Molecular Formula]
C12H6Cl4O2S | [MDL Number]
MFCD00018127 | [Molecular Weight]
356.05 | [MOL File]
116-29-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White, crystalline powder. Soluble in chloroform and aromatic hydrocarbons;
insoluble in water. | [Melting point ]
146.5-147.5° | [Boiling point ]
484.0±45.0 °C(Predicted) | [density ]
1.5630 (estimate) | [storage temp. ]
0-6°C | [form ]
neat | [color ]
White to off-white | [Water Solubility ]
50ug/L(10 ºC) | [Merck ]
13,9273 | [BRN ]
2292528 | [Henry's Law Constant]
6.9×103 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [Major Application]
agriculture
environmental | [InChI]
1S/C12H6Cl4O2S/c13-7-1-3-8(4-2-7)19(17,18)12-6-10(15)9(14)5-11(12)16/h1-6H | [InChIKey]
MLGCXEBRWGEOQX-UHFFFAOYSA-N | [SMILES]
Clc1ccc(cc1)S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl | [CAS DataBase Reference]
116-29-0(CAS DataBase Reference) | [NIST Chemistry Reference]
P-chlorophenyl, 2,4,5-trichlorophenyl sulfone(116-29-0) | [EPA Substance Registry System]
116-29-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN3077 9/PG 3 | [WGK Germany ]
3 | [RTECS ]
WR5850000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 | [Safety Profile]
Moderately toxic by
ingestion. Mildly toxic by slun contact. An
experimental teratogen. Used to control
worms in crops. When heated to
decomposition it emits highly toxic fumes of
Cland SOx. | [Hazardous Substances Data]
116-29-0(Hazardous Substances Data) | [Toxicity]
LD50 orally in rats: 556 mg/kg (Ben-dyke) |
| Hazard Information | Back Directory | [Chemical Properties]
White, crystalline powder. Soluble in chloroform and aromatic hydrocarbons;
insoluble in water. | [Uses]
Acaricide. Ovicide on deciduous fruits, citrus, cotton and other crops. | [Definition]
ChEBI: A sulfone that is diphenylsulfone in which one of the phenyl groups is substituted by chlorine at position 4, while the other is substituted by a chlorine at positions 2, 4, and 5. | [Production Methods]
Tetradifon is produced commercially through a multi-step synthesis involving chlorinated benzene derivatives and sulfonylation reactions, resulting in a stable organochlorine acaricide used in agriculture. The process begins with the preparation of 1,2,4-trichlorobenzene, which serves as a key intermediate. This compound undergoes sulfonylation with 4-chlorobenzenesulfonyl chloride to form the active ingredient tetradifon. | [Mechanism of action]
Non-systemic with larvicidal and ovicidal activity. Acts by inhibiting oxidative phosphorylation. Inhibitor of mitochondrial ATP synthase. | [IC 50]
Mite | [Pesticide Type]
Acaricide; Insecticide |
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