| Identification | Back Directory | [Name]
Withaphysalin E | [CAS]
118985-24-3 | [Synonyms]
Withaphysalin E
Ergosta-2,4,24-triene-18,26-dioic acid, 6,14,20,22-tetrahydroxy-1-oxo-, γ-lactone δ-lactone, (6β,22R)- | [Molecular Formula]
C28H34O7 | [MOL File]
118985-24-3.mol | [Molecular Weight]
482.57 |
| Chemical Properties | Back Directory | [Boiling point ]
747.0±60.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.58±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Withaphysalin E is a natural product that can be isolated from Physalis divericata. Withaphysalin E can be used in the study of non-small cell lung cancer[1][2]. | [References]
[1] Rao PC, et al. Cytotoxicity of withasteroids: withametelin induces cell cycle arrest at G2/M phase and mitochondria-mediated apoptosis in non-small cell lung cancer A549 cells. Tumour Biol. 2016 Sep;37(9):12579-12587. DOI:10.1007/s13277-016-5128-5
[2] Ma L, et al. Withaphysanolide A, a novel C-27 norwithanolide skeleton, and other cytotoxic compounds from Physalis divericata. Tetrahedron letters, 2007, 48(3): 449-452 |
|
|