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1191450-19-7

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1191450-19-7 Structure

1191450-19-7 Structure
IdentificationBack Directory
[Name]

Forodesine
[CAS]

1191450-19-7
[Synonyms]

Burixafor HBr
TG-0054 hydrobromide
Burixafor hydrobromide (TG-0054 hydrobromide)
Burixafor hydrobromide (Synonyms: TG-0054 hydrobromide)
[Molecular Formula]

C27H52BrN8O3P
[MDL Number]

MFCD31813774
[MOL File]

1191450-19-7.mol
[Molecular Weight]

647.64
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Solid
[color ]

Light yellow to yellow
[Water Solubility ]

Water : 50 mg/mL
Hazard InformationBack Directory
[Description]

Burixafor, also known as TG-0054, is an orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. Burixafor binds to the chemokine receptor CXCR4, thereby preventing the binding of stromal derived factor-1 (SDF-1 or CXCL12) to the CXCR4 receptor and subsequent receptor activation; this may the mobilization of hematopoietic stem and progenitor cells from the bone marrow into blood. Note: Elemental analysis showed it was a salt with 3 HBr and 3 water.
Spectrum DetailBack Directory
[Spectrum Detail]

Forodesine(1191450-19-7)1HNMR
1191450-19-7 suppliers list
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