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1191450-19-7

中文名称 BURIXAFOR HYDROBROMIDE
英文名称 Forodesine
CAS 1191450-19-7
分子式 C27H52BrN8O3P
分子量 647.64
MOL 文件 1191450-19-7.mol
1191450-19-7 结构式 1191450-19-7 结构式

基本信息

中文别名
化合物 T10635
英文别名
Burixafor HBr
TG-0054 hydrobromide
Burixafor hydrobromide (TG-0054 hydrobromide)
Burixafor hydrobromide (Synonyms: TG-0054 hydrobromide)

物理化学性质

储存条件-20°C储存
形态Solid
颜色Light yellow to yellow
水溶解性Water : 50 mg/mL

应用领域

用途一
Burixafor, also known as TG-0054, is an orally bioavailable inhibitor of CXC chemokine receptor 4 (CXCR4) with receptor binding and hematopoietic stem cell-mobilization activities. Burixafor binds to the chemokine receptor CXCR4, thereby preventing the binding of stromal derived factor-1 (SDF-1 or CXCL12) to the CXCR4 receptor and subsequent receptor activation; this may the mobilization of hematopoietic stem and progenitor cells from the bone marrow into blood. Note: Elemental analysis showed it was a salt with 3 HBr and 3 water.

常见问题列表

概述
Burixafor hydrobromide (TG-0054 hydrobromide) 是具有口服活性的、有效的 CXC 族趋化因子受体 4 (CXCR4) 的拮抗剂,是一种具有潜在研究脉络膜新生血管的抗血管生成剂。Burixafor hydrobromide (TG-0054 hydrobromide) 能够在猪心肌梗死模型中,动员间充质干细胞,减轻炎症反应,维持心脏的收缩功能。
BURIXAFOR HYDROBROMIDE价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2026/06/05HY-19867ABURIXAFOR HYDROBROMIDE
Burixafor hydrobromide
1191450-19-75 mg1000元
2026/06/05HY-19867ABURIXAFOR HYDROBROMIDE
Burixafor hydrobromide
1191450-19-710 mg1500元
2026/06/05HY-19867ABURIXAFOR HYDROBROMIDE
Burixafor hydrobromide
1191450-19-710 mM * 1 mL in Water1692元
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