120796-97-6

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120796-97-6 Structure

Identification	Back Directory
[Name] BIG ET-1 (1-38) (HUMAN)
[CAS] 120796-97-6
[Synonyms] ENDOTHELIN, BIG, HUMAN BIG ET-1 (1-38) (HUMAN) BIG ENDOTHELIN 38 HUMAN BIG ENDOTHELIN-1 (HUMAN) Endothelin 1 (human),big ENDOTHELIN, BIG 1-38, HUMAN BIG-ENDOTHELIN-I (1-38), HUMAN BIG ENDOTHELIN-1 (HUMAN, 1-38) BIG ENDOTHELIN-1 (1-38) (HUMAN) BIG ET-1 (1-38) (HUMAN) USP/EP/BP CSCSSLMDKECVYFCHLDIIWVNIPEHWPYGLGSPRS CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER-OH CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR- PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-VAL-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-ARG-SER(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11) Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
[Molecular Formula] C189H282N48O56S5
[MDL Number] MFCD00081408
[Molecular Weight] 4282.87

Chemical Properties	Back Directory
[storage temp. ] −20°C
[solubility ] Soluble in DMSO
[form ] Solid
[color ] White to off-white
[Sequence] Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-His-Val-Val-Pro-Tyr-Gly-Leu-Gly-Ser-Pro-Arg-Ser (Disulfide bridge: Cys1-Cys15; Cys3-Cys11)

Hazard Information	Back Directory
[Uses] Big Endothelin-1 (1-38), human is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide[1].
[References] [1] Marie-Hélène Fecteau, et al. Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo. Hypertension. 2005 Jul;46(1):87-92. DOI:10.1161/01.HYP.0000170460.24604.23

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