| Identification | Back Directory | [Name]
5H-Imidazo[4,5-c]pyridine-5-carboxamide, 6-[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]-3,4,6,7-tetrahydro-N-(1-methylethyl)-, (6S)- | [CAS]
1212663-24-5 | [Synonyms]
CBK289001
5H-Imidazo[4,5-c]pyridine-5-carboxamide, 6-[3-(1,3-benzodioxol-5-yl)-1,2,4-oxadiazol-5-yl]-3,4,6,7-tetrahydro-N-(1-methylethyl)-, (6S)- | [Molecular Formula]
C19H20N6O4 | [MOL File]
1212663-24-5.mol | [Molecular Weight]
396.4 |
| Hazard Information | Back Directory | [Description]
CBK289001 is an inhibitor of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity. | [Uses]
CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 μM, 4.21 μM and 14.2 μM, respectively[1]. | [References]
[1] Anja Reithmeier, et al. Identification of inhibitors of Tartrate-resistant acid phosphatase (TRAP/ACP5) activity by small-molecule screening. Chem Biol Drug Des. 2018 Jul;92(1):1255-1271. DOI:10.1111/cbdd.13187 |
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