| Identification | Back Directory | [Name]
ASC-69 (APY69) | [CAS]
1216665-50-7 | [Synonyms]
Apy69
ASC-69
ASC-69 (APY69)
2-[4-({4-[(5-Cyclopropyl-1H-pyrazol-3-yl)amino]-6-methylpyrimidin-2-yl}amino)phenyl]acetonitrile
Benzeneacetonitrile, 4-[[4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-methyl-2-pyrimidinyl]amino]- | [Molecular Formula]
C19H19N7 | [MDL Number]
MFCD28405131 | [MOL File]
1216665-50-7.mol | [Molecular Weight]
345.401 |
| Chemical Properties | Back Directory | [Boiling point ]
662.9±65.0 °C(Predicted) | [density ]
1.381±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.27±0.10(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
ASC-69 (APY69)is a potent and promising?PD-1/PD-L1 small-molecule inhibitor[1]. | [References]
[1] Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64(22):16687-16702. DOI:10.1021/acs.jmedchem.1c01422 |
|
| Company Name: |
A.J Chemicals
|
| Tel: |
91-9810153283 |
| Website: |
www.ajchemicals.com |
| Company Name: |
AstaTech, Inc
|
| Tel: |
(215) 785 3197 |
| Website: |
www.astatechinc.com |
|