| Identification | Back Directory | [Name]
L-Lysinamide, L-valyl-L-glutaminyl-L-arginyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-valyl-L-tryptophyl-L-arginyl-L-isoleucyl-L-arginyl- | [CAS]
1224095-25-3 | [Synonyms]
IDR 1002
L-Lysinamide, L-valyl-L-glutaminyl-L-arginyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-valyl-L-tryptophyl-L-arginyl-L-isoleucyl-L-arginyl- | [Molecular Formula]
C79H130N26O13 | [MOL File]
1224095-25-3.mol | [Molecular Weight]
1652.04 |
| Chemical Properties | Back Directory | [density ]
1.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.31±0.46(Predicted) | [color ]
White to off-white | [Sequence]
Val-Gln-Arg-Trp-Leu-Ile-Val-Trp-Arg-Ile-Arg-Lys-NH2 |
| Hazard Information | Back Directory | [Description]
IDR 1002 is a synthetic cationic innate defense regulator peptide that increases the numbers of neutrophils and monocytes in mouse peritoneum and protects against S. aureus and E. coli infections in mice. | [Uses]
IDR-1002 is an anti-infective peptide that enhances the ability of human monocytes to migrate toward chemokines on fibronectin. IDR-1002 also induces adhesion and activation of β1-integrin, a mechanism that promotes monocyte recruitment[1]. | [storage]
-20°C | [References]
[1] Madera L, et al. Synthetic immunomodulatory peptide IDR-1002 enhances monocyte migration and adhesion on fibronectin. J Innate Immun. 2012;4(5-6):553-68. DOI:10.1159/000338648 |
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| Company Name: |
Fuan Bio
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| Tel: |
15002819872 |
| Website: |
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