| Identification | More | [Name]
(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride | [CAS]
126330-90-3 | [Synonyms]
2-PIPERAZINECARBOXYLIC ACID, DIHYDROCHLORIDE, (2R)- 2-PIPERAZINECARBOXYLIC ACID, DIHYDROCHLORIDE, (2S)- 2-PIPERAZINECARBOXYLIC ACID, (S)-, DIHYDROCHLORIDE PIPERAZINECARBOXYLIC ACID, (R)-, DIHYDROCHLORIDE (R)-(+)-2-PIPERAZINECARBOXYLIC ACID DIHYDROCHLORIDE (R)-2-PIPERAZINECARBOXYLIC ACID DIHYDROCHLORIDE (R)-PIPERAZINE-2-CARBOXYLIC ACID 2HCL (R)-(+)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE (R)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE (S)-(-)-2-PIPERAZINECARBOXYLIC ACID DIHYDROCHLORIDE (S)-PIPERAZINE-2-CARBOXYLIC ACID 2HCL (S)-(-)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE (S)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE (r)-piperazine-2-carbxylicaciddihydrochloride (R)-(+)-PIPERAZINE-2-CARBOXYLIC ACID DIHCL (R)-Piperazin-2-carbonsaeure2HCl (R)-(+)-PIPERAZINE-2-CARBOXYLIC ACID DIHYDROCHLORIDE,98% 3-PIPERAZINE CARBOXYLIC ACID HCL 2-(R)-Piperazine carboxylic acid 2HCl | [Molecular Formula]
C5H12Cl2N2O2 | [MDL Number]
MFCD01632104 | [Molecular Weight]
203.07 | [MOL File]
126330-90-3.mol |
| Chemical Properties | Back Directory | [Melting point ]
ca 265℃ | [Fp ]
143.5℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
solid | [Appearance]
White to off-white Solid | [Optical Rotation]
[α]20/D +5±1°, c = 1% in H2O | [Detection Methods]
T | [InChI]
InChI=1/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H/t4-;;/s3 | [InChIKey]
WNSDZBQLMGKPQS-RZFWHQLPSA-N | [SMILES]
[C@H]1(C(=O)O)NCCNC1.Cl.Cl |&1:0,r| | [CAS DataBase Reference]
126330-90-3(CAS DataBase Reference) | [Storage Precautions]
Store under inert gas |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [F ]
3-10 | [HS Code ]
29335990 | [Storage Class]
13 - Non Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Uses]
(R)-2-Piperazinecarboxylic acid dihydrochloride can be used as a starting material for the synthesis of (R)-enantiomers of anthramycin analogs, which are potential antiproliferative agents. It can also be employed in the preparation of piperazinemethanol chiral ligands, which can be utilized in the enantioselective borane reduction of aromatic ketones, ketimine, and oxime ether. | [Synthesis]
As a method for the preparation of racemic 2-piperazine carboxylic acids by optical splitting, it is known to use cyclic camphorsulfonic acid as a splitting agent, racemic 2-piperazine carboxylic acids and cyclic camphorsulfonic acid are made to be dissol |
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