| Identification | Back Directory | [Name]
N-cyclopropyl-4-[8-(oxan-4-ylmethylamino)-6-[(1,1,1-trifluoro-2-methylpropan-2-yl)amino]imidazo[1,2-b]pyridazin-3-yl]benzamide | [CAS]
1263423-94-4 | [Synonyms]
Mps1-IN-4
N-cyclopropyl-4-[8-(oxan-4-ylmethylamino)-6-[(1,1,1-trifluoro-2-methylpropan-2-yl)amino]imidazo[1,2-b]pyridazin-3-yl]benzamide | [Molecular Formula]
C26H31F3N6O2 | [MOL File]
1263423-94-4.mol | [Molecular Weight]
516.559 |
| Hazard Information | Back Directory | [Uses]
Mps1-IN-4 is a selective Monopolar spindle 1 (Mps1) inhibitor with antiproliferative activity for cancer research[1]. | [References]
[1] Ken-Ichi Kusakabe, et al. Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity. J Med Chem. 2015 Feb 26;58(4):1760-75. DOI:10.1021/jm501599u |
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