| Identification | Back Directory |  [Name]
  SeMilicoisoflavone B |  [CAS]
  129280-33-7 |  [Synonyms]
  PSX005 SeMilicoisoflavone B 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)- |  [Molecular Formula]
  C20H16O6 |  [MDL Number]
  MFCD28100710 |  [MOL File]
  129280-33-7.mol |  [Molecular Weight]
  352.34 |  
 | Chemical Properties | Back Directory |  [Boiling point ]
  615.5±55.0 °C(Predicted) |  [density ]
  1.443±0.06 g/cm3(Predicted) |  [storage temp. ]
  Store at -20°C |  [solubility ]
  Soluble in DMSO |  [form ]
  Solid |  [pka]
  6.43±0.20(Predicted) |  [color ]
  Light yellow to green yellow |  [biological source]
  plant |  [Water Solubility ]
  water: slightly soluble |  
 | Hazard Information | Back Directory |  [Uses]
  It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. |  [Definition]
  ChEBI: A member of the class of 7-hydroxyisoflavones that is 2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one substituted by hydroxy groups at positions 5, 7 and 8'. It has been isolated from Glycyrrhiza uralensis. |  [Biological Activity]
  Semilicoisoflavone B:
 - Suppresses proinflammatory cytokine productiondownregulates TLR4 expressionand diminishes reactive oxygen species generation in vitro.
 - Inhibits the growth and division of cancer cells by triggering apoptosis and arresting the cell cycleoffering potential for effective tumor therapy.
 - Restricts Caco-2 cell proliferationsuggesting potential for metabolic syndrome therapy.
 
 
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