| Identification | Back Directory | [Name]
LICOCHALCONEC | [CAS]
144506-14-9 | [Synonyms]
LICOCHALCONEC
4,4'-Dihydroxy-2-Methoxy-3-prenylchalcone
(E)-3-[4-hydroxy-2-methoxy-3-(3-methylbut-2-enyl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
2-Propen-1-one,3-[4-hydroxy-2-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-1-(4-hydroxyphenyl)-,(2E)- | [Molecular Formula]
C21H22O4 | [MDL Number]
MFCD20527293 | [MOL File]
144506-14-9.mol | [Molecular Weight]
338.4 |
| Chemical Properties | Back Directory | [Boiling point ]
536.1±50.0 °C(Predicted) | [density ]
1.181±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
-20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
powder | [pka]
7.82±0.15(Predicted) | [color ]
Yellow | [biological source]
plant | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
1S/C21H22O4/c1-14(2)4-11-18-20(24)13-8-16(21(18)25-3)7-12-19(23)15-5-9-17(22)10-6-15/h4-10,12-13,22,24H,11H2,1-3H3/b12-7+ | [InChIKey]
WBDNTJSRHDSPSR-KPKJPENVSA-N | [SMILES]
O(C)c1c(c(ccc1\C=C\C(=O)c2ccc(cc2)O)O)CC=C(C)C |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of licorice. | [Uses]
It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research. | [Biological Activity]
According to the existing researchLicochalcone C may have an effect on processes related to inflammation and cell death regulation by inhibiting the expression of TNF-αCaspase and Bcl-2/Bax | [target]
TNF-α | Caspase | Bcl-2/Bax |
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