| Identification | Back Directory | [Name]
S-Acetyl-PEG3-Azido | [CAS]
1310827-26-9 | [Synonyms]
S-Acetyl-PEG3-N3
S-Acetyl-PEG3-Azido
S-Acetyl-PEG3-azide
S-acetyl-dPEG4-azido
AZIDO-PEG3-THIOACETATE
Acetylthio-PEG3-C2-Azide
S-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl] Ethanethioate
Ethanethioic Acid S-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl] Ester | [Molecular Formula]
C10H19N3O4S | [MDL Number]
MFCD22201539 | [MOL File]
1310827-26-9.mol | [Molecular Weight]
277.34 |
| Hazard Information | Back Directory | [Description]
S-Acetyl-PEG3-azide is a PEG linker containing an azide group and a sulfur acetyl group. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. S-Acetyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
TCI Europe
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| Tel: |
320-37350700 |
| Website: |
https://www.tcichemicals.com/de/de/index.html |
| Company Name: |
TCI AMERICA
|
| Tel: |
800-4238616 |
| Website: |
https://www.tcichemicals.com/en/us/index.html |
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